Author Interview Archive

YouTube Click here to view Mayo Clinic Proceedings author interviews and editorial commentaries on YouTube, organized by issues, searchable by topic.

2022

Dr Carl (Chip) Lavie examines the effects of obesity over time on the incidents of high-risk metabolic phenotypes that confer risks for metabolic syndrome and cardiometabolic diseases.

Read the article, Trends in Metabolic Phenotypes According to Body Mass Index Among US Adults, 1999-2018

Ms Rewan Abdelwahab offers solutions to medical institutions for improving their diversity and inclusion by accommodating religious headwear in the surgical suite to enhance medical education around the globe.

Read the article, Medical Practice Should Not Require the Stripping Away of One's Self

Dr Sunil Sahai and the SPAQI group seek to obtain consensus on the perioperative management of cardiovascular medications based on available literature and personal experience.

Read the article, Preoperative Management of Cardiovascular Medications: A Society for Perioperative Assessment and Quality Improvement (SPAQI) Consensus Statement

Dr John Olynyk finds arthritis is strongly associated with the presence of advanced hepatic fibrosis in HFE hemochromatosis

Read the article, Arthritis Prediction of Advanced Hepatic Fibrosis in HFE Hemochromatosis

Mr Joshua Trockel notes an adverse impact of work on physicians' personal relationships being associated with unsolicited patient complaints.

Read the article, Assessment of the Relationship Between an Adverse Impact of Work on Physicians' Personal Relationships and Unsolicited Patient Complaints

Dr Mohamed Dafaalla finds 2 causes for women to be less likely to survive out-of-hospital cardiac arrest: Longer arrival to hospital times and less aggressive treatments once in the hospital.

Read the article, Women Are Less Likely to Survive AMI Presenting With Out-of-Hospital Cardiac Arrest: A Nationwide Study

Dr Nischal Ranganath examines the virology and epidemiology of monkeypox, as well as provides an overview of treatment and preventative strategies.

Read the article, Monkeypox 2022: Gearing up for Another Potential Public Health Crisis

Dr Raymund Razonable finds the use of monoclonal antibody treatment to be highly effective in reducing hospitalizations and death during the Delta surge of the COVID-19 pandemic.

Read the article, Curbing the Delta Surge: Clinical Outcomes after Treatment with Bamlanivimab-Etesevimab, Casirivimab-Imdevimab or Sotrovimab for COVID-19

Dr Rita Basu describes the leading causes of non-alcoholic fatty liver disease and its progression to nonalcoholic steatohepatitis.

Read the article, Nonalcoholic Fatty Liver Disease: Review of Management for Primary Care Providers

Dr Christina de Souza e Silva finds machine learning can be applied to create a simple prognostic model in which maximal exercise capacity is further suggested to be one of the most powerful predictors of mortality in CAD.

Read the article, Prediction of Mortality in Coronary Artery Disease: Role of Machine Learning and Maximal Exercise Capacity

Dr Richard Milani finds 3 health barriers — financial stress, patient activation, and health literacy — to be the key drivers for disparity in managing hypertension in diverse populations. Available at:

Read the article, Racial Differences and Social Determinants of Health in Achieving Hypertension Control

Dr Api Chewcharat finds lower dietary calcium, potassium, caffeine, phytate, and fluid intake are all associated with higher odds of incident symptomatic kidney stones.

Read the article, Dietary Risk Factors for Incident and Recurrent Symptomatic Kidney Stones

Ms Hsin-Yi Huang finds clopidogrel use is associated with significantly lower risk when compared to aspirin use in patients with ischemic stroke in patients age 80 years or older.

Read the article, Effectiveness and Safety of Clopidogrel vs Aspirin in Elderly Patients With Ischemic Stroke

Dr Abhishek Deshmukh tracked physical activity trends for patients who had implanted electronic cardiac devices during the first few months of the pandemic when social distancing was initiated.

Read the article, Physical Activity in Cardiac Implantable Electronic Device Recipients During the COVID-19 Pandemic

Dr Linda Russell and Dr Angela Edwards offer practical information for medication use in perioperative medical management.

Read the article, Preoperative Management of Medications for Rheumatologic and HIV Diseases: Society for Perioperative Assessment and Quality Improvement (SPAQI) Consensus Statement

Dr Kyla Lara-Breitinger and Dr Sorin Pislaru find that patients with multiple comorbidities are less likely to be at highest risk from tricuspid regurgitation.

Read the article, Tricuspid Regurgitation Impact on Outcomes (TRIO): A Simple Clinical Risk Score

Dr Glenn Gaesser finds total grain intake, defined as the consumed sum of refined and whole grains, is associated with lower risk of type 2 diabetes.

Read the article, Refined Grain Intake and Risk of Type 2 Diabetes

Dr David Holmes, Jr, notes it is common for left atrial appendage "occlusion" for stroke prevention to be incomplete, which has important implications as the LAA has been found to be the source of 90% of embolic strokes in patients with non-valvular atrial fibrillation.

Read the article, Left Atrial Appendage Occlusion, A Misnomer?: Where Do We Go From Here?

Dr Ahmed Ibrahim Ahmed finds coronary artery calcium scores and exercise capacity have complementary risk stratifying roles in coronary artery disease.

Read the article, Prognostic Interplay Between Coronary Artery Calcium Scoring and Cardiorespiratory Fitness: The CAC-FIT Study

Dr Kukbin Choi finds CABG has been shown to be an alternative treatment option for patients in their 80s with increased long-term survival outcomes.

Read the article, Coronary Artery Bypass Grafting in Octogenarians- Risks Outcomes and Trends in 1283 Consecutive Patients

Dr Sandra Herrmann and Dr Yi Lin note clinicians should be on alert for acute kidney injury in patients receiving CAR-T therapy to provide preemptive management and reduce risk.

Read the article, Incidence and Risk Factors for Acute Kidney Injury Following Chimeric Antigen Receptor T-Cell (CAR-T) Therapy

Dr Sherri Braksick suggests that tailoring less invasive tests for patients with trigeminal neuropathy could decrease discomfort and reduce costs as a first-line approach in many cases.

Read the article, Etiologies and Utility of Diagnostic Tests in Trigeminal Neuropathy

Dr Boris Fishman finds an invasive approach has survival benefit among octogenarians presenting with NSTEMI, suggesting treatment for these patients should be similar to younger patients.

Read the article, Invasive Management in Older Adults (≥80) With Non-ST Elevation Myocardial Infarction

Ms Natalie Caine and Dr Vijay Shah describe the four pillars framework to achieve the 2030 Mayo Clinic vision.

Read the article, A 2030 Vision for the Mayo Clinic Department of Medicine

Dr. Karna Sundsted finds patients with chronic gastrointestinal, hepatic or renal disease are at risk for multiple perioperative complications and benefit from comprehensive preoperative evaluation.

Read the article, Preoperative Evaluation and Management of Patients with Select Chronic Gastrointestinal, Liver, and Renal Diseases

Dr Joseph Ahn uses a machine algorithm to assist in distinguishing between two GI conditions that are different but that present with similar symptoms.

Read the article, Machine Learning Techniques Differentiate Alcohol-Associated Hepatitis From Acute Cholangitis In Patients With Systemic Inflammation And Elevated Liver Enzymes

Dr Julien Dang provided for the first-time data guiding antibiotic therapy management of renal Cyst Infection in patients with Autosomal Dominant Polycystic Kidney Disease.

Read the article, Efficacy of Prolonged Antibiotic Therapy for Renal Cyst Infections in Polycystic Kidney Disease

Dr Yara Moustafa and Dr Mohit Chauhan look at 2 national databases that indicated a trend for increased use and misuse of ADHD medications.

Read the article, Attention Deficit Hyperactivity Disorder Overdiagnosis and Overprescriptions: Medicalization of Distractions

Dr Hatem Amer, Dr Martin Kumnig, and Dr Sheila Jowsey-Gregoire share the process for developing an international workgroup for teams interested in reconstructive transplantation.

Read the article, The Chauvet Workgroup: A Resource for the Psychosocial Aspects of Reconstructive Transplantation

Dr Jeffrey Geske assesses whether right ventricular enlargement and right ventricular dysfunction adversely affect prognosis in hypertrophic cardiomyopathy.

Read the article, Right Ventricular Enlargement and Dysfunction are Associated With Increased All-Cause Mortality in Hypertrophic Cardiomyopathy

Dr Saraschandra Vallabhajosyula finds newer P2Y12 inhibitors are associated with lower rates of early and one-year mortality in patients experiencing acute MI with cardiac arrest or cardiogenic shock, and receiving dual antiplatelet therapy.

Read the article, Newer P2Y12 Inhibitors vs Clopidogrel in Acute Myocardial Infarction With Cardiac Arrest or Cardiogenic Shock: A Systematic Review and Meta-analysis

Dr Pramod Guru and Dr Abhishek Giri share their experiences with ultra-low dose (25 mg) systemic tissue plasminogen activator (tPA) in a series of four patients with high-risk sub-massive pulmonary embolism.

Read the article, Ultra-Low-Dose Systemic Tissue Plasminogen Activator (tPA) in High-Risk Sub-Massive Pulmonary Embolism

Dr Lester Leung finds a natural language processing algorithm designed to identify silent brain infarcts and white matter disease from neuroimaging reports can identify patients at risk.

Read the article, Risk Factors for Silent Brain Infarcts and White Matter Disease in a Real-world Cohort Identified by Natural Language Processing

Dr Chelsee Jensen and Dr Eric Tichy discuss the use of biosimilars at Mayo Clinic.

Read the article, Implementing and Optimizing Biosimilar Use at Mayo Clinic

Dr Jad Sfeir explains the pathophysiology and clinical implications of age-related bone loss.

Read the article, Skeletal Aging

Dr Patricia Pellikka finds the prevalence of mitral annulus calcification was 23%; moderate or greater mitral valve dysfunction was more than twice as prevalent in patients with mitral annulus calcification.

Read the article, Prevalence and Natural History of Mitral Annulus Calcification and Related Valve Dysfunction

Dr Mark Linzer discusses ways clinicians can ease the burden of treatment for patients struggling with complicated comorbidities and competing social conditions that could make adhering to medical care plans difficult.

Read the article, Reducing the Burden of Treatment: How Our Patients Feel About What We Ask of Them: A "Less is More" Perspective

Dr Salma Iftikhar stresses the importance of the use of medical interpreters for patients with limited English proficiency.

Read the article, Enhancing Medical Communication and Care Through Professional Medical Interpreters

Dr Timucin Taner finds complication rates for living kidney donors to be very low when viewed in the long term.

Read the article, Complications After Hand-Assisted Laparoscopic Living Donor Nephrectomy

Dr Pierre Deharo finds surgical revascularization should be individually considered as an alternative to percutaneous coronary intervention in patients with STEMI.

Read the article, Myocardial Revascularization Strategies in ST Elevation Myocardial Infarction Without Urgent Revascularization: Insight from a Nationwide Study

Dr Luc Jansen, Dr Maarten van Schijndel, and Dr Roger Kathol offer insights into the causes, needs, and solutions for patients needing integrated medical and psychiatric care.

Read the article, Specialty Psychiatric Services in US Emergency Departments and General Hospitals: Results From a Nationwide Survey

Dr Rachel Robbins and Dr Drew Helmer offer answers for patients struggling with chronic multisymptom illness and the challenges it presents.

Read the article, The Management of Chronic Multisymptom Illness: Synopsis of the 2021 US Department of Veterans Affairs and US Department of Defense Clinical Practice Guideline

Dr Wayne Gao and Mr Min-Kuang Tsai find 150 minutes per week of physical activity provided benefit for a significant reduction in the risk of end-stage renal disease.

Read the article, Role of Physical Activity in Lowering Risk of End-Stage Renal Disease

Dr Erika Weil suggests that AI–enabled ECG for AF not only predicts atrial fibrillation, but also detects other non-atrial fibrillation cardiac-disease markers that share associations with small vessel cerebrovascular disease and cognitive decline.

Read the article, Artificial Intelligence–Enabled Electrocardiogram for Atrial Fibrillation Identifies Cognitive Decline Risk and Cerebral Infarcts

Dr Emily Olson notes a decrease in weekly incidents of role misidentification for female and underrepresented resident physicians after the addition of role-clarifying identification badges.

Read the article, Physician Identification Badges: A Multispecialty Quality Improvement Study to Address Professional Misidentification and Bias

Dr Christine Sinsky and Dr Colin West examine the tremendous financial burden experienced in health care related to physician burnout.

Read the article, Health Care Expenditures Attributable to Primary Care Physician Overall and Burnout-Related Turnover: A Cross- sectional Analysis

Dr Ruba Saadeh and Dr Maria Alice Willrich find kappa free light chains in cerebrospinal fluid can be used in place of oligoclonal bands-testing to support the diagnosis of multiple sclerosis.

Read the article, CSF Kappa Free Light Chains: Cutoff Validation for Diagnosing Multiple Sclerosis

Dr David Kent describes a risk-prediction model that is fully compatible with the EHR to predict a 3-year diabetes risk in the general population.

Read the article, An Electronic Health Record-Compatible Model to Predict Personalized Treatment Effects From the Diabetes Prevention Program: A Cross-Evidence Synthesis and Approach Using Clinical Trial and Real-World Data

Dr Shreya Shah proposes utilization of prospective, real-time prediction models based on EHRs to address preventable hospital and ER visits on a population level.

Read the article, Predicting Avoidable Health Care Utilization: Practical Considerations for Artificial Intelligence/Machine Learning Models in Population Health

Dr Biff Palmer finds overconsumption of nutrients can be a precursor to metabolic inflexibility, mitochondrial dysfunction, and dysregulation of metabolic health.

Read the article, Metabolic Flexibility and Its Impact on Health Outcomes

Dr Javaid Nauman notes using the Personal Activity Intelligence metric provides scientific evidence that structured exercise and increased lifestyle physical activity confer a survival benefit.

Read the article, Association Between Personal Activity Intelligence and Mortality: Population-Based China Kadoorie Biobank Study

Dr Jwan Naser found AI algorithms were able to identify patients with Graves disease at risk of atrial fibrillation, low ejection fraction and changes in menstruation and fertility.

Read the article, Artificial Intelligence Application in Graves� Disease: Atrial Fibrillation, Heart Failure and Menstrual Changes

Dr. Moo-Nyun Jin finds no excess risk of primary cardiac arrest was present among individuals with activity level above five times the recommended minimum.

Read the article, Association of Physical Activity With Primary Cardiac Arrest Risk in the General Population: A Nationwide Cohort Study of the Dose-Response Relationship

Mr Derrick Gibson finds no significant differences in the incidences of opioid-related ED visits or hospitalizations among older cancer survivors.

Read the article, Risk of an Opioid-Related Emergency Department Visit or Hospitalization Among Older Breast, Colorectal, Lung, and Prostate Cancer Survivors

Dr Amy Kunchok notes autoimmune/paraneoplastic encephalitis/encephalopathy, though uncommon, is an increasingly recognized condition with several antibody biomarkers.

Read the article, Autoimmune/Paraneoplastic Encephalitis Antibody Biomarkers: Frequency, Age, and Sex Associations

Mr Tyler Schneider and Dr Mina Tadrous compare the trends and discrepancies in insulin drug pricing between Canada and the United States.

Read the article, Comparisons of Insulin Spending and Price Between Canada and the United States

Dr Ravindra Ganesh finds that most patients with long COVID syndrome are female and most have elevated interleukin-6 levels and myalgia.

Read the article, The Female-Predominant Persistent Immune Dysregulation of Post-COVID Syndrome

Dr Camille Kezer develops the Mortality Index for Alcohol-Associated Hepatitis, which accurately predicts 30-day mortality in patients with alcohol-associated hepatitis.

Read the article, The Mortality Index for Alcohol-Associated Hepatitis: A Novel Prognostic Score

Ms Shreeya Joshee, Dr Christopher Chang, and Dr Nikhil Vatti review the pulmonary, cardiovascular, neurological, and hematological systems primarily affected by post-COVID-19 sequelae.

Read the article, Long-Term Effects of COVID-19

Dr Tait Shanafelt reviews job-related stress for physicians when compared to other careers throughout the first 6 months of the pandemic.

Read the article, Changes in Burnout and Satisfaction With Work-Life Integration in Physicians and the General US Working Population Between 2011 and 2020

Dr June Tome and Dr Amrit Kamboj provide practical advice for diagnosing and treating nausea and vomiting.

Read the article, A Practical Five-Step Approach to Nausea and Vomiting

Dr Yu-Sheng Lin finds cardio-selective beta-blocker treatment during hospitalization and after discharge superior to non-selective beta-blockers in COPD patients after miocardial infarction.

Read the article, Cardioselective Versus Nonselective β-Blockers After Myocardial Infarction in Adults With Chronic Obstructive Pulmonary Disease

Dr Leonard Kaminsky provides updated measures for patients and clinicians to better understand and measure health outcomes like cardiovascular disease risks.

Read the article, Updated Reference Standards for Cardiorespiratory Fitness Measured with Cardiopulmonary Exercise Testing: Data from the Fitness Registry and the Importance of Exercise National Database (FRIEND)

Dr Gonzalo Barge-Caballero finds increased survival rates in patients treated with beta-blockers for transthyretin amyloid cardiomyopathy.

Read the article, Beta-Blocker Exposure and Survival in Patients With Transthyretin Amyloid Cardiomyopathy

Dr William Padula recommends aligning nutrition, mobility, and moisture care teams to reduce iatrogenic injuries.

Read the article, Complexity Bias in the Prevention of Iatrogenic Injury: Why Specific Harms May Inhibit Performance

Dr Raymund Razonable reviews the reasons for the COVID-19 delta variant to be more virulent.

Read the article, Effectiveness of Monoclonal Antibodies in Preventing Severe COVID-19 With Emergence of the Delta Variant

Dr Surendra Dasari finds mass spectrometry is a more specific and sensitive diagnostic tool for detecting plasma cell disorders.

Read the article, Detection of Plasma Cell Disorders by Mass Spectrometry: A Comprehensive Review of 19,523 Cases

Dr Chansong Choi finds patients whose etiology of liver disease is secondary to alcohol- associated cirrhosis have worse survival following discharge from the ICU compared with patients with other etiologies.

Read the article, Relationship Between Etiology of Cirrhosis and Survival Among Patients Hospitalized in Intensive Care

Dr Irbaz Bin Riaz suggests direct oral anti-coagulant therapy may improve efficacy compared to dalteparin without sacrificing safety in many cases.

Read the article, Direct Oral Anticoagulants Compared With Dalteparin for Treatment of Cancer-Associated Thrombosis: A Living, Interactive Systematic Review and Network Meta-analysis

Dr Kasey Boehmer examines the progress made for adapting systems to support minimally disruptive medicine for patients with complicated chronic medical conditions.

Read the article, Minimally Disruptive Medicine: Progress 10 Years Later

Dr Stella Hartono and Dr Alexander Meves review preclinical studies of vascular endothelial growth factor as a potential treatment for the acute consequences of sunburn.

Read the article, Vascular Endothelial Growth Factor as an Immediate-Early Activator of UV-Induced Skin Injury

Dr Adebamike Oshunbade finds a history hypertensive pregnancy is associated with nearly a 5-times greater risk for chronic kidney disease later in life.

Read the article, Hypertensive Diseases in Pregnancy and Kidney Function Later in Life: The Genetic Epidemiology Network of Arteriopathy (GENOA) Study

Dr Kerri Palamara shares strategies institutions can use for instilling hope and fostering creativity to reduce physician burnout.

Read the article, Four Key Questions Leaders Can Ask to Support Clinicians During the COVID-19 Pandemic Recovery Phase

Dr Alanna Chamberlain finds younger populations to be at greater risk for chronic conditions in socioeconomically disadvantaged locations.

Read the article, Associations of Neighborhood Socioeconomic Disadvantage With Chronic Conditions by Age, Sex, Race, and Ethnicity in a Population-Based Cohort

Dr LaPrincess Brewer examines the root causes of the nearly double rate of cardiovascular mortality among African-American adults in Minnesota.

Read the article, Association of Cardiovascular Disease Risk Factors with Socio-demographics and Health Beliefs Among a Community-based Sample of African-Americans in Minnesota

Dr Sergio Schwartzman provides insight on the practical use of a graphical roadmap to assist health care providers in the identification of axSpA in clinical practice.

Read the article, A Road Map of the Axial Spondyloarthritis Continuum

Dr Raymund Razonable shares two screening tools to prioritize subgroups of patients with COVID-19 who are at the highest risks of hospitalization and to target them for early treatment.

Read the article, Clinical Prioritization of Anti-Spike Monoclonal Antibody Treatment of Mild to Moderate COVID-19

Dr Mohamed Mohamed finds higher comorbidity burden was associated with increased risk of in-hospital mortality and acute ischemic stroke, but not procedure-related or device-related complications.

Read the article, The Impact of Charlson Comorbidity Index on De Novo Cardiac Implantable Electronic Device Procedural Outcomes in the United States

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