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Opioids
2 Results
- Letter to the Editor
Additional Safety Considerations Before Prescribing Opioids to Manage Restless Legs Syndrome
Mayo Clinic ProceedingsVol. 93Issue 7p955Published in issue: July, 2018- Aaron S. Geller
Cited in Scopus: 0Silber et al1 are commended for espousing the merit of low and stable dose opioid treatment of refractory restless legs syndrome (RLS) given the risks of suicide and severely compromised quality of life if untreated. Opioid agreements reduce risks of RLS treatment with opioids as agreements mandate drug testing as well as frequent query of prescription drug monitoring programs. - Letter to the Editor
Benzodiazepine Oncogenesis as Mediated via Diminished Restorative Sleep Effected Sympathoadrenal Activation
Mayo Clinic ProceedingsVol. 87Issue 10p1034–1035Published in issue: October, 2012- Aaron S. Geller
Cited in Scopus: 1The valuable cohort contribution by Kao et al1 associating narcotic zolpidem consumption with heightened iatrogenic malignancy risks would be considerably more compelling if accompanied by proposition of a distinct plausible pathophysiologic mechanism. The most favorably received mechanism would define associations between the physiologic effects of zolpidem that are common to other pharmacologic agents and diagnoses that effect similar intermediary stepwise events epidemiologically linked to oncogenesis.