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- SUPPLEMENT ARTICLE
Recommendations for the Pharmacological Management of Neuropathic Pain: An Overview and Literature Update
Mayo Clinic ProceedingsVol. 85Issue 3SupplementS3–S14Published in issue: March, 2010- Robert H. Dworkin
- Alec B. O'Connor
- Joseph Audette
- Ralf Baron
- Geoffrey K. Gourlay
- Maija L. Haanpää
- and others
Cited in Scopus: 1016The Neuropathic Pain Special Interest Group of the International Association for the Study of Pain recently sponsored the development of evidence-based guidelines for the pharmacological treatment of neuropathic pain. Tricyclic antidepressants, dual reuptake inhibitors of serotonin and norepinephrine, calcium channel α2-δ ligands (ie, gabapentin and pregabalin), and topical lidocaine were recommended as first-line treatment options on the basis of the results of randomized clinical trials. Opioid analgesics and tramadol were recommended as second-line treatments that can be considered for first-line use in certain clinical circumstances.
