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Opioids
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- Review
Opioid Use in Fibromyalgia: A Cautionary Tale
Mayo Clinic ProceedingsVol. 91Issue 5p640–648Published online: March 11, 2016- Don L. Goldenberg
- Daniel J. Clauw
- Roy E. Palmer
- Andrew G. Clair
Cited in Scopus: 55Multiple pharmacotherapies are available for the treatment of fibromyalgia (FM), including opioid analgesics. We postulate that the mechanism of action of traditional opioids predicts their lack of efficacy in FM. Literature searches of the MEDLINE and Cochrane Library databases were conducted using the search term opioid AND fibromyalgia to identify relevant articles, with no date limitations set. Citation lists in returned articles and personal archives of references were also examined for additional relevant items, and articles were selected based on the expert opinions of the authors.
