- A 56-year-old man presented with a 3-week history of copious, watery, and foul-smelling diarrhea as well as very mild abdominal cramping, nonbilious vomiting, and a 25-lb weight loss. The patient had a history of familial glomerosclerosis, which required renal transplantation 3 years earlier. His symptoms were unaffected by changes in diet. He noticed mucus in his stools, which appeared like flecks of tissue paper. He denied odynophagia, hematochezia, melena, pain with defecation, fever, or night sweats.
- A 51-year-old man with a medical history of mild osteoarthritis went to the emergency department for the evaluation of worsening, bilateral injected, painful eyes of 1-month duration associated with the development of a nonproductive cough and nonexertional chest pain for 1 week. He had been treated with topical moxifloxacin for conjunctivitis without improvement 3 weeks before presentation. Subsequently, he developed a nonproductive cough, right ear pain with diminished hearing, chest pain that worsened with inspiration, and posttussive, nonbloody emesis.
- A 23-year-old man presented to an outside hospital with a 3-day history of dark-colored urine, yellow discoloration of the eyes, and pain in the chest and lumbar area. He denied having confusion, fever, chills, or light-colored stools. He reported consuming small amounts of alcohol once a month and never using tobacco or illicit drugs. His medical history was positive only for anxiety, which was not treated pharmacologically. The patient stated that he had not taken nonprescription medications, herbal supplements, or prescribed medication in the preceding year.
- A 24-year-old man presented to the emergency department with a 2-day history of progressively worsening chest pain and shortness of breath. He described the pain as a sharp, substernal sensation occurring at rest, exacerbated by deep inspiration or lying flat on his back, and alleviated by sitting upright leaning forward. He did not report radiation to the neck or left arm. Associated symptoms included nausea, vomiting, and nonproductive cough, which began 2 days before the onset of chest pain. His medical history was notable for systemic lupus erythematosus (SLE) complicated by nephritis and congestive heart failure with reduced ejection fraction.
- A 56-year-old woman presented to the outpatient clinic in October with a 1-week history of fatigue, night sweats, and cough productive of yellow sputum. She had no associated fever, chills, chest pain, or shortness of breath and no recent history of travel, hospitalization, or exposure to people with similar symptoms. Her medical history was notable only for hyperlipidemia and hypertension treated with pravastatin and atenolol. She was a lifetime nonsmoker who did not drink alcohol or use illicit substances.
- A 50-year-old man with a history of angioimmunoblastic T-cell lymphoma presented to the emergency department with malaise and low back pain and was hospitalized with the diagnosis of new-onset acute kidney injury (AKI). The patient had a history of autologous stem cell transplant and disease recurrence, for which he underwent salvage chemotherapy with dexamethasone, 2 doses of cytarabine, and 1 dose of cisplatin 4 days before the current presentation. He also had hyperlipidemia but did not take medication.