- A 28-year-old man with no significant medical history presented to his primary care provider with 4 months of progressive left-testicular enlargement. His symptoms were not associated with pain, dysuria, fever, weight loss, or recent trauma. He was sexually active only with his wife. He endorsed using condoms for contraception and denied unsafe sexual practices.
- A 65-year-old man presented with a several-month history of generalized weakness, diffuse arthralgia, and progressive acrocyanosis and necrosis requiring amputation of several digits. The patient also reported weight loss and night sweats during the previous several months but no fever or chills. His medical history was notable for coronary artery disease, ischemic cardiomyopathy (with ejection fraction of 40%), and type 2 diabetes mellitus. He had a distant smoking history (40 pack-years, quit over 20 years previously) and was a recently retired coal mine worker.
- An 86-year-old man with a history of atrial fibrillation (AF) and lower extremity venous stasis ulcers presented to our primary care clinic to establish care. He had dyspnea on exertion that had worsened from baseline limiting his capacity to perform basic activities of daily living including getting dressed. He also had progressive lower extremity swelling for several years and had received ongoing treatment of his venous stasis ulcers from a local vascular surgeon.