- “When I use a word,” Humpty Dumpty said, in rather a scornful tone, “it means just what I choose it to mean—neither more nor less.”“The question is,” said Alice, “whether you can make words mean so many different things.”Lewis Carroll, Through the Looking Glass
- Although thrombolysis has become standard treatment for patients with coronary artery thrombosis and myocardial infarction, the use of thrombolytic therapy in patients with acute strokes is a much more recent and more uncertain strategy. The attractiveness of thrombolytic drugs for stroke is their potential to reverse even severe neurologic deficits by lysing occlusive thrombi that deprive vital brain regions of blood. In this issue of the Mayo Clinic Proceedings (pages 1005 to 1013), Wijdicks and colleagues from the Mayo Clinic stroke service describe their recent experience with use of intra-arterial delivery of the thrombolytic drug urokinase to treat nine patients who had acute occlusions of the basilar artery and severe neurologic deficits.
- In this issue of the Mayo Clinic Proceedings (pages 1027 to 1039), Brown and colleagues from the Mayo Clinic stroke service present a detailed, carefully considered, timely algorithm that incorporates their current advice for assessment and management of patients with minor strokes and transient ischemic attacks (TIAs). The report includes the rationale behind the practical advice and provides support for their positions from studies in the literature.
- The Stroke Council of the American Heart Association (AHA) recently announced the creation of the Robert G. Siekert Young Investigator Award. This award for meritorious stroke research will be inaugurated at the 14th International Joint Conference on Stroke and the Cerebral Circulation, to be held in San Antonio in February 1989. The recipient will be chosen on the basis of material submitted for presentation at that meeting. This award, named for one of the important leaders and a former chairman of the Stroke Council and the first program chairman of the International Stroke Conference, represents a landmark in the history of stroke research, a coming of age.