Editorials
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- Editorial
Explaining Unexplained Hypoglycemia Due To Insulin Analogs
Mayo Clinic ProceedingsVol. 97Issue 11p1966–1968Published in issue: November, 2022- Marilyn F. Augustine
- Katie King
- Y. Victoria Zhang
Cited in Scopus: 0Hypoglycemia is a potentially life-threatening condition that requires urgent medical attention. Most hypoglycemia in patients with diabetes is related to medication use, and recent studies have indicated the contributions of insulin analogs in cases of hypoglycemia.1,2 Even in patients without diabetes, it is important to exclude insulin administration as a cause of hypoglycemia, yet detection of insulin analogs is not straightforward. The small structural changes that result in favorable pharmacokinetics of insulin analogs also affect the detection of analog insulin by immunoassays, culminating in varying results from different commercially available assays.