- Cardiac amyloidosis (CA) remains a challenging disease to detect and to diagnose. Recent advancements in treatment necessitate more rapid diagnosis so that treatment can be initiated as early as possible. In this issue of Mayo Clinic Proceedings, Bézard et al1 report on the real-life evaluation of an algorithm for the diagnosis of CA. The authors propose a “one-stop shop” approach to the diagnosis of CA by performing 4 tests simultaneously at the first day of a visit: serum and urine screening for monoclonal protein (MCP), nuclear cardiac scintigraphy, salivary gland biopsy, and DNA TTR testing.
- We think sometimes that poverty is only being hungry, naked, and homeless. The poverty of being unwanted, unloved, and uncared for is the greatest poverty. Mother Teresa
- Coronary atherosclerosis risk is strongly associated with elevated levels of low-density lipoprotein cholesterol (LDL-C).1 Elevated serum triglycerides are also associated with increased coronary risk, but controversy exists over whether triglycerides (TGs) themselves are atherogenic or merely reflect a surrogate marker for other cardiometabolic disorders including low high-density lipoprotein cholesterol (HDL-C), diabetes mellitus, and obesity.2-5 An important clinical question is whether patients at high atherogenic risk, currently on statin medication, need additional specific treatment for hypertriglyceridemia if it is present.
- Zhou Enlai (the first premier of the People’s Republic of China), when asked his opinion of the impact of the French Revolution (of 1789) in an interview conducted in 1968 during the height of the Paris student riots, is reported to have stated that it was “too early to tell.”
- A bird doesn’t sing because it has an answer, it sings because it has a songMaya Angelou
- All truths are easy to understand once they are discovered; the point is to discover them.—Galileo Galilei (1564-1642)