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Disease Progression and End-Stage Renal Disease in Diverse Glomerulopathies
Mayo Clinic ProceedingsVol. 93Issue 2p133–135Published online: January 24, 2018- Karl A. Nath
- Fernando C. Fervenza
Cited in Scopus: 2Chronic kidney disease (CKD) is not a functionally static process but rather a potentially progressive one that may culminate in end-stage renal disease (ESRD). The onset of ESRD is a turning point in the course of CKD because ESRD substantially alters the patient's lifestyle and imposes increased morbidity and mortality in patients so afflicted. For most patients, ESRD is managed by in-center hemodialysis, a treatment modality that obligates, among other requirements, the placement and functionality of a vascular access for hemodialysis; the need to travel thrice weekly to the dialysis center; thrice-weekly hemodialysis treatments lasting 3 or more hours; tolerance to the recurrent lassitude and generalized lack of well-being often experienced after each hemodialysis treatment; and restricted intake of fluids and assorted dietary constituents.
