A 36-year-old male patient newly diagnosed as having human immunodeficiency virus/acquired immunodeficiency syndrome with a CD4 count on presentation of 3 cells/μL presented with an oral lesion. This lesion was previously thought to be a dental abscess that persisted despite incision and drainage (Figure). The lesion had a raised nodular appearance, was purple, and seemed to be of vascular origin. This was highly suspicious for Kaposi sarcoma. This suspicion was confirmed by a biopsy showing tumor cells positive for CD31 and human herpesvirus 8.
Erythema migrans is a characteristic rash that appears in approximately 70% to 80% of patients with Lyme disease.1 The ring-shaped rash usually appears at the site of the tick bite within the first 2 weeks and expands outward.