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Pruritic Skin Eruption in a Pregnant Woman
Mayo Clinic ProceedingsVol. 96Issue 2p427–428Published in issue: February, 2021- Joshua K. Hanson
- Julia S. Lehman
Cited in Scopus: 0A 21-year-old gravida1para0 previously healthy pregnant woman at 37 weeks’ gestation had a pruritic skin eruption that initially involved the umbilicus and spread to affect much of the abdomen, lower back, and extremities. Her pregnancy was otherwise uncomplicated. Urticarial lesions with rare blisters were noted (Figure 1). Skin biopsy revealed spongiosis and mixed dermal inflammation with eosinophils, whereas direct immunofluorescence revealed linear deposition of C3 along the basement membrane zone (BMZ) (Figure 2).