Abstract
Objective
Patients and Methods
Results
Conclusion
Abbreviations and Acronyms:
BMI (body mass index), CVD (cardiovascular disease), DFTJ (Dongfeng-Tongji cohort), FBG (fasting blood glucose), HbA1c (hemoglobin A1c), NHANES (National Health and Nutrition Examination Survey), NIH (National Institutes of Health)Purchase one-time access:
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Footnotes
For editorial comment, see page 11
Grant Support: This work was supported by the National Natural Science Foundation of China (81930124, 82021005, and 82073554), Fundamental Research Funds for the Central Universities (2021GCRC075 and 2021GCRC076), Hubei Province Science Fund for Distinguished Young Scholars (2021CFA048), and China Postdoctoral Science Foundation (2021M691129).
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- Brave New World: Improving Obesity and Preventing Cardiovascular DiseaseMayo Clinic ProceedingsVol. 98Issue 1
- PreviewFor several decades, obesity and type 2 diabetes (T2D) have been rising in tandem so that today, they are worsening global pandemics with debilitating, expensive, and often lethal complications. The prevalence of T2D in the United States has risen more than 10-fold from 2.5 million in 1959 to more than 25 million in 2022.1 During the same time frame, obesity has risen 4-fold, so that now it affects 40% of US adults and is the leading cause of preventable disease and premature mortality. About 90% of people with T2D are overweight or obese, and traditional drugs for T2D, including insulin, sulfonylureas, and thiazolidinediones, cause further weight gain.
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