Abstract
Objective
To examine the combined association of five healthy lifestyle behaviors with hearing
loss (HL) in the UK Biobank cohort, established between 2006 and 2010 in the United
Kingdom.
Methods
This longitudinal analysis included 61,958 participants aged 40 to 70 years from April
2007 to December 2016. The healthy behaviors examined were: never smoking, high level
of physical activity, high diet quality, moderate alcohol intake, and optimal sleep.
Hearing loss was self-reported at baseline and in any physical exam during the follow-up.
Results
Over a median follow-up of 3.9±2.5 years, 3072 (5.0%) participants reported incident
HL. After adjustment for potential confounders, including age, social factors, exposure
to high-intensity noise, ototoxic medication, and comorbidity, the HRs of HL associated
with having 1, 2, 3, and 4 to 5 vs 0 behaviors were: 0.85 (95% CI, 0.75 to 0.96),
0.85 (95% CI, 0.75 to 0.96), 0.82 (95% CI, 0.71 to 0.94), and 0.80 (95% CI, 0.67 to
0.97), respectively (P for trend, 0.02). We estimated that the population attributable risk percent for
not adhering to any five low-risk lifestyle behaviors was 15.6%.
Conclusion
In this large study, an increasing number of healthy behaviors was associated with
decreased risk of HL.
Abbreviations and Acronyms:
BMI (body mass index), DASH (dietary approaches to stop hypertension), HL (hearing loss)To read this article in full you will need to make a payment
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Article Info
Publication History
Published online: June 13, 2022
Publication stage
In Press Corrected ProofFootnotes
Grant Support: UK Biobank was established by the Wellcome Trust medical charity, Medical Research Council, Department of Health, Scottish Government, and the Northwest Regional Development Agency. It has also had funding from the Welsh Government, British Heart Foundation, Cancer Research UK, and Diabetes UK. This study has been funded by Instituto de Salud Carlos III through the FIS project 20/01040 (Instituto de Salud Carlos III, State Secretary of R+D+I), and cofunded by a European Regional Development Fund, “A way of shaping Europe.” The funding agencies had no role in the study design, data analysis, interpretation of results, writing of the report, and in the decision to submit the article for publication.
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