Abstract
Risk stratification of pulmonary embolism (PE) is vital for clinical management. While
low-risk and high-risk PE management are clearly defined in many societal guidelines,
the management of moderate-risk, also called submassive, PE remains unsettled. There is a subgroup of patients with submassive PE that progress
to the severe category despite receiving systemic anticoagulation. The role of thrombolysis
in the management of submassive PE remains to be established. We share our experience
with ultra-low-dose (25-mg) systemic tissue plasminogen activator in a series of 4
patients with high-risk submassive PE.
Abbreviations and Acronyms:
CT (computed tomography), LV (left ventricular), PE (pulmonary embolism), PESI (Pulmonary Embolism Severity Index), RV (right ventricular), tPA (tissue plasminogen activator)To read this article in full you will need to make a payment
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