Abstract
Objective
To study the patient profiles and the prognostic impact of type 2 myocardial infarction
(MI) on outcomes of acute ischemic stroke (AIS).
Methods
The National Readmission Database 2018 was queried for patients with primary AIS hospitalizations
with and without type 2 MI. Baseline characteristics, inpatient outcomes, and 30-day
all-cause readmissions between cohorts were compared.
Results
Of 587,550 AIS hospitalizations included in the study, 4182 (0.71%) had type 2 MI.
Patients with type 2 MI were older (73.6 years vs 70.1 years; P<.001) and more likely to be female (52% vs 49.7%; P<.001), and they had a higher prevalence of heart failure (32.6% vs 15.5%; P<.001), atrial fibrillation (38.5% vs 24.2%; P<.001), prior MI (8.8% vs 7.7%; P<.001), valvular heart disease (17% vs 9.8%; P<.001), peripheral vascular disease (12.2% vs 9.2%; P<.001), and chronic kidney disease (24.4% vs 16.7%; P<.001). Compared with patients without type 2 MI, AIS patients with type 2 MI had
significantly higher in-hospital mortality (adjusted odds ratio [aOR], 1.96; 95% CI,
1.65 to 2.32), poor functional outcome (aOR, 1.80; 95% CI, 1.62 to 2.00), more hospital
costs (adjusted parameter estimate, $5618; 95% CI, $4480 to $6755), higher rate of
discharge to a facility (aOR, 1.70; 95% CI, 1.52 to 1.90), increased length of stay
(adjusted parameter estimate, 2.22; 95% CI, 1.72 to 2.72), and higher rate of 30-day
all-cause readmissions (aOR, 1.38; 95% CI, 1.18 to 1.60).
Conclusion
Type 2 MI in patients hospitalized with AIS is associated with poor prognosis and
higher resource utilization.
Abbreviations and Acronyms:
AF (atrial fibrillation), AHRQ (Agency for Health Care Research and Quality), AIS (acute ischemic stroke), CKD (chronic kidney disease), HCUP (Healthcare Cost and Utilization Project), HF (heart failure), ICD-10-CM (International Classification of Diseases), Tenth Revision (Clinical Modification), LOS (length of stay), MI (myocardial infarction), MT (mechanical thrombectomy), NRD (Nationwide Readmission Database), OR (odds ratio)To read this article in full you will need to make a payment
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Article Info
Publication History
Published online: April 26, 2022
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