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Metaplastic Breast Cancer

      Which of the following statements regarding breast metaplastic carcinoma is correct?
      • a.
        Metaplastic carcinoma is a common type of breast carcinoma
      • b.
        Metaplastic carcinoma is usually positive for hormonal receptors
      • c.
        Metaplastic carcinoma is a heterogeneous group of invasive breast carcinomas with squamous and/or mesenchymal-like morphology
      • d.
        Metaplastic carcinoma often occurs in young women
      Answer: c. Metaplastic carcinoma is a heterogeneous group of invasive breast carcinomas with squamous and/or mesenchymal-like morphology.

      References

        • Schroeder M.C.
        • Rastogi P.
        • Geyer Jr., C.E.
        • Miller L.D.
        • Thomas A.
        Early and locally advanced metaplastic breast cancer: presentation and survival by receptor status in Surveillance, Epidemiology, and End Results (SEER) 2010–2014.
        Oncologist. 2018; 23: 481-488
        • Downs-Kelly E.
        • Nayeemuddin K.M.
        • Albarracin C.
        • Wu Y.
        • Hunt K.K.
        • Gilcrease M.Z.
        Matrix-producing carcinoma of the breast: an aggressive subtype of metaplastic carcinoma.
        Am J Surg Pathol. 2009; 33: 534-541