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Renal Leiomyoma

      Which of the following is most accurate?
      • a.
        Renal leiomyomas and leiomyosarcomas can occur in the kidney
      • b.
        Renal smooth muscle tumors occur exclusively in men
      • c.
        Renal leiomyomas do not express hormone receptors by immunohistochemistry
      • d.
        Renal leiomyomas occur exclusively in hereditary leiomyomatosis and renal cell carcinoma (HLRCC)
      In the kidney, leiomyomas and leiomyosarcomas can occur.
      • Gupta S.
      • Jiminez R.E.
      • Folpe A.L.
      • Cheville J.C.
      Renal leiomyoma and leiomyosarcoma: a study of 57 cases.
      Renal smooth-muscle tumors can arise in both men and women.
      • Gupta S.
      • Jiminez R.E.
      • Folpe A.L.
      • Cheville J.C.
      Renal leiomyoma and leiomyosarcoma: a study of 57 cases.
      In addition, similar-appearing tumors, particularly in a capsular location with HMB45 immunopositivity, are now considered to be leiomyomatous angiomyolipomas.
      • Tamboli P.
      • Ro J.Y.
      • Amin M.B.
      • Ligato S.
      • Ayala A.G.
      Benign tumors and tumor-like lesions of the adult kidney. Part II: Benign mesenchymal and mixed neoplasms, and tumor-like lesions.

      References

        • Gupta S.
        • Jiminez R.E.
        • Folpe A.L.
        • Cheville J.C.
        Renal leiomyoma and leiomyosarcoma: a study of 57 cases.
        Am J Surg Pathol. 2016; 40: 1557-1563
        • Tamboli P.
        • Ro J.Y.
        • Amin M.B.
        • Ligato S.
        • Ayala A.G.
        Benign tumors and tumor-like lesions of the adult kidney. Part II: Benign mesenchymal and mixed neoplasms, and tumor-like lesions.
        Adv Anat Pathol. 2000; 7: 47-66