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In reply—The Mona Lisa Decrypted: Another Premise

      The intrigue of the Mona Lisa continues to inspire as Dr Mullany provides yet another explanation for the enigmatic picture. Given the vast number of differential diagnoses already proposed previously and enumerated in our review,
      • Mehra M.R.
      • Campbell H.R.
      The Mona Lisa decrypted: allure of an imperfect reality.
      this new assertion that a neurological injury or central nervous system malady defines the observed posture does deserve some discussion. Whether you examine the main painting or the deciphered one as interpreted by Bruno Mottin a decade ago,
      • Austen I.
      New look at Mona Lisa yields some new secrets.
      the positions of the hands do not clearly advise in favor of a clear neurological insult. The painting was assuredly done with multiple sittings and not a single one and thus it is understandable that Leonardo da Vinci captured multiple phases and ended with what he thought was the most relaxed posture. The position of the right hand is consistent with a relaxed posture and even one that denotes some degree of flaccidity as would be encountered with hypothyroidism. To postulate a diagnosis of a neurovascular insult is beyond the depictions visually apparent and would likely be a bit of a stretch based on observed findings, although it certainly is thought provoking. I would draw attention to an aphorism in medicine, attributed to Dr Theodore Woodward at the University of Maryland School of Medicine, who instructed his medical interns: “When you hear hoofbeats, think of horses not zebras.”
      • Wikipedia
      Zebra (medicine).

      References

        • Mehra M.R.
        • Campbell H.R.
        The Mona Lisa decrypted: allure of an imperfect reality.
        Mayo Clin Proc. 2018; 93: 1325-1327
        • Austen I.
        New look at Mona Lisa yields some new secrets.
        New York Times. September 27, 2006;
        • Wikipedia
        Zebra (medicine).
        https://en.wikipedia.org/wiki/Zebra_(medicine)
        Date accessed: January 9, 2019