Advertisement
Mayo Clinic Proceedings Home

Perihilar Cholangiocarcinoma

      This image is a cross section of a perihilar cholangiocarcinoma.
      Which of the following statements is most accurate about cholangiocarcinoma?
      • a.
        The incidence of cholangiocarcinoma has decreased markedly over the past few decades
      • b.
        Categorizing cholangiocarcinomas according to their anatomical location (intrahepatic, perihilar, and distal) has epidemiological and prognostic implications
      • c.
        Cholangiocarcinoma is more common than hepatocellular carcinoma
      • d.
        Cholangiocarcinomas are indolent tumors and rarely associated with metastases
      Answer: b. Categorizing cholangiocarcinomas according to their anatomical location (intrahepatic, perihilar, and distal) has epidemiologic and prognostic implications.
      • Rizvi S.
      • Khan S.A.
      • Hallemeier C.L.
      • Kelley R.K.
      • Gores G.J.
      Cholangiocarcinoma – evolving concepts and therapeutic strategies.
      The incidence of cholangiocarcinoma has increased over the past few decades.
      • Rizvi S.
      • Khan S.A.
      • Hallemeier C.L.
      • Kelley R.K.
      • Gores G.J.
      Cholangiocarcinoma – evolving concepts and therapeutic strategies.
      Perihilar cholangiocarcinomas are more common than intrahepatic and distal tumors, but epidemiologic features differ, reflecting different underlying diseases. Hepatocellular carcinoma is the most common primary liver carcinoma. Cholangiocarcinomas are aggressive tumors, and patients often present with advanced disease.
      • Rizvi S.
      • Khan S.A.
      • Hallemeier C.L.
      • Kelley R.K.
      • Gores G.J.
      Cholangiocarcinoma – evolving concepts and therapeutic strategies.

      Reference

        • Rizvi S.
        • Khan S.A.
        • Hallemeier C.L.
        • Kelley R.K.
        • Gores G.J.
        Cholangiocarcinoma – evolving concepts and therapeutic strategies.
        Nat Rev Clin Oncol. 2018; 15: 95-111