Abstract
Objective
To determine population-based incidence estimates of basal cell carcinoma (BCC) and
cutaneous squamous cell carcinoma (cSCC).
Patients and Methods
We reviewed the medical records of a population-based cohort diagnosed with nonmelanoma
skin cancer between January 2, 2000, and December 31, 2010. The age- and sex-adjusted
incidence rates were calculated and compared with estimates from previous periods.
Results
The age-adjusted BCC incidence (cases per 100,000 person-years) was 360.0 (95% CI,
342.5-377.4) in men and 292.9 (95% CI, 278.6-307.1) in women. The age-adjusted cSCC
incidence (cases per 100,000 person-years) was 207.5 (95% CI, 193.9-221.1) in men
and 128.8 (95% CI, 119.4-138.2) in women. From years 1976 to 1984 to years 2000 to
2010, the age- and sex-adjusted incidence (cases per 100,000 person-years) of BCC
increased from 222.0 (95% CI, 204.5-239.5) to 321.2 (95% CI, 310.3-332.2) and that
of cSCC from 61.8 (95% CI, 52.3-71.4) to 162.5 (95% CI, 154.6-170.3). Over time, the
anatomical distribution of BCC shifted from the head and neck to the torso and that
of cSCC shifted from the head and neck to the extremities.
Conclusion
The incidences of BCC and cSCC are increasing, with a disproportionate increase in
cSCC relative to BCC. There is also a disproportionate increase in the incidence of
both tumors in women, as well as a shift of anatomical distributions.
Abbreviations and Acronyms:
BCC (basal cell carcinoma), cSCC (cutaneous squamous cell carcinoma), IQR (interquartile range), NMSC (nonmelanoma skin cancer)To read this article in full you will need to make a payment
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Article Info
Publication History
Published online: May 15, 2017
Footnotes
Grant Support: This study was made possible by the Rochester Epidemiology Project (grant no. R01-AG034676; Principal Investigators: Walter A. Rocca, MD, MPH, and Jennifer L. St Sauver, PhD).
Identification
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