Patients and Methods
Abbreviations and Acronyms:ALS (amyotrophic lateral sclerosis), MCI (mild cognitive impairment), NA (not applicable), PD (Parkinson disease), REP (Rochester Epidemiology Project)
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Grant Support: This study was made possible by the Rochester Epidemiology Project (grant number R01-AG034676; Principal Investigators: Walter A. Rocca, MD, MPH, and Jennifer St Sauver, PhD).
Potential Competing Interests: Dr Boeve has received personal fees from the Scientific Advisory Board of the Tau Consortium and Isis Pharmaceuticals and grants from GE Healthcare, the National Institutes of Health, the Mangurian Foundation, Cephalon Inc, FORUM Pharmaceuticals, and C2N Diagnostics, all outside the present work. Dr Mielke serves as a consultant for Lysosomal Therapeutics Inc and holds a grant from the Michael J. Fox Foundation, both outside the present work.