Abstract
Objective
To estimate the age- and sex-adjusted incidence of melanoma in adults 61 years or
older in Olmsted County, Minnesota, from 1970 through 2009.
Patients and Methods
Using Rochester Epidemiology Project resources, 397 patients were identified who were
61 years or older and who received a first lifetime diagnosis of melanoma from January
1, 1970, through December 31, 2009, in Olmsted County. The incidence of melanoma and
the overall and disease-specific survival rates were compared by age, sex, year of
diagnosis, and stage of disease.
Results
From 1970 through 2009, age- and sex-adjusted incidence increased significantly (P<.001) from 17.0 (95% CI, 8.6-25.4) to 124.6 (95% CI, 108.9-140.3) per 100,000 person-years,
with a 4-fold increase in women and a more than 11-fold increase in men. In men, incidence
rates increased with age (P<.001) and over time (P<.001). In women, incidence rates increased over time (P<.001) but were constant across all age groups studied (P=.90). The dramatic increase in the incidence of melanoma was observed mainly for
stages 0 and I tumors in both men and women (>55-fold increase). Disease-specific
survival increased across the decades (P<.001); when year of diagnosis was compared to mortality, hazard ratios were 0.94
(95% CI, 0.90-0.99; P=.010) and 0.93 (95% CI, 0.89-0.98; P=.006) for men and women, respectively.
Conclusion
The incidence of melanoma in older men and women increased significantly over the
past 4 decades in Olmsted County, with men experiencing higher rates of increase than
did women.
Abbreviations and Acronyms:
IQR (interquartile range), REP (Rochester Epidemiology Project), SEER (Surveillance, Epidemiology, and End Results)To read this article in full you will need to make a payment
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Article Info
Publication History
Published online: September 28, 2016
Footnotes
Grant Support: This study was made possible by the Rochester Epidemiology Project (grant no. R01-AG034676; Principal Investigators: Walter A. Rocca, MD, MPH, and Jennifer St Sauver, PhD).
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