Patients and Methods
Abbreviations and Acronyms:CVD (cardiovascular disease), CVRF (cardiovascular risk factor), MET (metabolic equivalent of task), OR (odds ratio), Q (quintile)
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- Minimum amount of physical activity for reduced mortality and extended life expectancy: a prospective cohort study.Lancet. 2011; 378: 1244-1253
- Exercise is medicine: at any dose?.JAMA. 2015; 314: 1915-1916
- Exercise and physical activity in the prevention and treatment of atherosclerotic cardiovascular disease: a statement from the Council on Clinical Cardiology (Subcommittee on Exercise, Rehabilitation, and Prevention) and the Council on Nutrition, Physical Activity, and Metabolism (Subcommittee on Physical Activity).Circulation. 2003; 107: 3109-3116
- Statement on exercise: benefits and recommendations for physical activity programs for all Americans. a statement for health professionals by the Committee on Exercise and Cardiac Rehabilitation of the Council on Clinical Cardiology, American Heart Association.Circulation. 1996; 94: 857-862
- Reduced disability and mortality among aging runners: a 21-year longitudinal study.Arch Intern Med. 2008; 168: 1638-1646
- Increased life expectancy of world class male athletes.Med Sci Sports Exerc. 1993; 25: 237-244
- Mortality of French participants in the Tour de France (1947-2012).Eur Heart J. 2013; 34: 3145-3150
Centers for Disease Control and Prevention, US Department of Health and Human Services. 2008 Physical activity guidelines for Americans: fact sheet for health professionals on physical activity guidelines for adults. http://www.cdc.gov/physicalactivity/downloads/pa_fact_sheet_adults.pdf. Accessed March 30, 2015.
- 2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.J Am Coll Cardiol. 2014; 63: 2960-2984
Global strategy on diet, physical activity and health: physical activity and adults. World Health Organization website. http://www.who.int/dietphysicalactivity/factsheet_adults/en. Accessed July 10, 2015.
- Dose of jogging and long-term mortality: the Copenhagen City Heart Study.J Am Coll Cardiol. 2015; 65: 411-419
- Frequent physical activity may not reduce vascular disease risk as much as moderate activity: large prospective study of women in the United Kingdom.Circulation. 2015; 131: 721-729
- 2011 Compendium of Physical Activities: a second update of codes and MET values.Med Sci Sports Exerc. 2011; 43: 1575-1581
- Dose response between physical activity and risk of coronary heart disease: a meta-analysis.Circulation. 2011; 124: 789-795
- Leisure-time running reduces all-cause and cardiovascular mortality risk.J Am Coll Cardiol. 2014; 64: 472-481
- Physical activity, all-cause mortality, and longevity of college alumni.N Engl J Med. 1986; 314: 605-613
- Minimal amount of exercise to prolong life: to walk, to run, or just mix it up?.J Am Coll Cardiol. 2014; 64: 482-484
- Physical activity for health: what kind? how much? how intense? on top of what?.Annu Rev Public Health. 2011; 32: 349-365
- Leisure time physical activity and mortality: a detailed pooled analysis of the dose-response relationship.JAMA Intern Med. 2015; 175: 959-967
- Sudden cardiac death in the older athlete.J Am Coll Cardiol. 2015; 65: 493-502
- Triggering of acute myocardial infarction by heavy physical exertion: protection against triggering by regular exertion: determinants of Myocardial Infarction Onset Study Investigators.N Engl J Med. 1993; 329: 1677-1683
- Are there deleterious cardiac effects of acute and chronic endurance exercise?.Physiol Rev. 2016; 96: 99-125
- Persistent and reversible cardiac dysfunction among amateur marathon runners.Eur Heart J. 2006; 27: 1079-1084
- Exercise and the heart: the good, the bad, and the ugly.Eur Heart J. 2015; 36: 1445-1453
- Can intensive exercise harm the heart? you can get too much of a good thing.Circulation. 2014; 130: 992-1002
- Longevity of endurance skiers.Med Sci Sports. 1974; 6: 49-51
- Survival of the fittest: retrospective cohort study of the longevity of Olympic medallists in the modern era.BMJ. 2012; 345: e8308
- Effect of moderate to vigorous physical activity on all-cause mortality in middle-aged and older Australians.JAMA Intern Med. 2015; 175: 970-977
- Dose of jogging: mortality versus longevity.J Am Coll Cardiol. 2015; 65: 2672-2673
- Observational research methods. research design II: cohort, cross sectional, and case-control studies.Emerg Med J. 2003; 20: 54-60
Grant Support: The work of T.M.H.E. was supported by a European Commission Horizon 2020 grant (Marie Sklodowska-Curie Fellowship 655502).
Potential Competing Interests: Dr Thompson reports receiving research grants from the National Institutes of Health, Genomas, Aventis, Regeneron, and Sanofi; serving as a consultant for AstraZeneca, Regeneron, Merck, Genomas, Abbott, Sanofi, and Pfizer; receiving speaker honoraria from Merck and AstraZeneca; and owning stock in General Electric, JA Wiley Publishing, J&J, and Abbott.