- Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group
KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease.
Kidney Inter. 2013; 3: 1-150- Reese P.P.
- Cappola A.R.
- Shults J.
- et al.
Physical performance and frailty in chronic kidney disease.
Am J Nephrol. 2013; 38: 307-315Relevance of albumin in modern critical care medicine.
Best Pract Res Clin Anaesthesiol. 2009; 23: 183-191The clinical significance of gastrointestinal changes with aging.
Curr Opin Clin Nutr Metab Care. 2008; 11: 651-660Nephrotic syndrome in adults.
BMJ. 2008; 336: 1185-1189- Mangoni A.A.
- Jackson S.H.
Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications.
Br J Clin Pharmacol. 2004; 57: 6-14Age-related changes in pharmacokinetics.
Curr Drug Metab. 2011; 12: 601-610Pharmacology and toxicology of mycophenolate in organ transplant recipients: an update.
Arch Toxicol. 2014; 88: 1351-1389- Keller F.
- Maiga M.
- Neumayer H.H.
- Lode H.
- Distler A.
Pharmacokinetic effects of altered plasma protein binding of drugs in renal disease.
Eur J Drug Metab Pharmacokinet. 1984; 9: 275-282Liver physiology and liver diseases in the elderly.
World J Gastroenterol. 2013; 19: 8459-8467Drug therapy in the elderly.
Exp Gerontol. 2004; 39: 1731-1738Polymorphism of human cytochrome P450 2D6 and its clinical significance: Part I.
Clin Pharmacokinet. 2009; 48: 689-723- Samer C.F.
- Lorenzini K.I.
- Rollason V.
- Daali Y.
- Desmeules J.A.
Applications of CYP450 testing in the clinical setting.
Mol Diagn Ther. 2013; 17: 165-184- Dreisbach A.W.
- Lertora J.J.
The effect of chronic renal failure on drug metabolism and transport.
Expert Opin Drug Metab Toxicol. 2008; 4: 1065-1074- Lindeman R.D.
- Tobin J.
- Shock N.W.
Longitudinal studies on the rate of decline in renal function with age.
J Am Geriatr Soc. 1985; 33: 278-285- Glassock R.J.
- Winearls C.
Ageing and the glomerular filtration rate: truths and consequences.
Trans Am Clin Climatol Assoc. 2009; 120: 419-428- Matzke G.R.
- Aronoff G.R.
- Atkinson Jr., A.J.
- et al.
Drug dosing consideration in patients with acute and chronic kidney disease-a clinical update from Kidney Disease: Improving Global Outcomes (KDIGO).
Kidney Int. 2011; 80: 1122-1137- Glassock R.J.
- Winearls C.G.
eGFR: Readjusting its rating.
Clin J Am Soc Nephrol. 2009; 4: 867-869- Farag A.
- Garg A.X.
- Li L.
- Jain A.K.
Dosing errors in prescribed antibiotics for older persons with CKD: a retrospective time series analysis.
Am J Kidney Dis. 2014; 63: 422-428- Corsonello A.
- Pedone C.
- Lattanzio F.
- et al.
Agreement between equations estimating glomerular filtration rate in elderly nursing home residents and in hospitalised patients: Implications for drug dosing.
Age Ageing. 2011; 40: 583-589- Corsonello A.
- Pedone C.
- Incalzi R.A.
Age-related pharmacokinetic and pharmacodynamic changes and related risk of adverse drug reactions.
Curr Med Chem. 2010; 17: 571-584- Gianni M.
- Bosch J.
- Pogue J.
- et al.
Effect of long-term ACE-inhibitor therapy in elderly vascular disease patients.
Eur Heart J. 2007; 28: 1382-1388- Chaudhry K.N.
- Chavez P.
- Gasowski J.
- Grodzicki T.
- Messerli F.H.
Hypertension in the elderly: some practical considerations.
Cleve Clin J Med. 2012; 79: 694-704- Eichhorn E.J.
- Gheorghiade M.
Digoxin.
Prog Cardiovasc Dis. 2002; 44: 251-26671-year-old man with chronic kidney failure and sudden change of mental status.
Mayo Clin Proc. 2009; 84: e5-e8- Beijer H.J.M.
- de Blaey C.J.
Hospitalisations caused by adverse drug reactions (ADR): a meta-analysis of observational studies.
Pharm World Sci. 2002; 24: 46-54- Cantú T.G.
- Ellerbeck E.F.
- Yun S.W.
- Castine S.D.
- Kornhauser D.M.
Drug prescribing for patients with changing renal function.
Am J Hosp Pharm. 1992; 49: 2944-2948- Sharif-Askari F.S.
- Syed Sulaiman S.A.
- Saheb Sharif-Askari N.
- Al Sayed Hussain A.
Development of an adverse drug reaction risk assessment score among hospitalized patients with chronic kidney disease.
PLoS One. 2014; 9: e95991- Son H.
- Lee D.
- Lim L.A.
- Jang S.B.
- Roh H.
- Park K.
Development of a pharmacokinetic interaction model for co-administration of simvastatin and amlodipine.
Drug Metab Pharmacokinet. 2014; 29: 120-128- Vidal L.
- Shavit M.
- Fraser A.
- Paul M.
- Leibovici L.
Systematic comparison of four sources of drug information regarding adjustment of dose for renal function.
BMJ. 2005; 331: 263- Verbeeck R.K.
- Musuamba F.T.
Pharmacokinetics and dosage adjustment in patients with renal dysfunction.
Eur J Clin Pharmacol. 2009; 65: 757-773- American Geriatrics Society 2012 Beers Criteria Update Expert Panel
American Geriatrics Society updated Beers Criteria for potentially inappropriate medication use in older adults.
J Am Geriatr Soc. 2012; 60: 616-631- Gallagher P.
- Ryan C.
- Byrne S.
- Kennedy J.
- O’Mahony D.
STOPP (Screening Tool of Older Person’s Prescriptions) and START (Screening Tool to Alert doctors to Right Treatment): consensus validation.
Int J Clin Pharmacol Ther. 2008; 46: 72-83- Patterson S.M.
- Cadogan C.A.
- Kerse N.
- et al.
Interventions to improve the appropriate use of polypharmacy for older people.
Cochrane Database Syst Rev. 2014; 10: CD008165- Susantitaphong P.
- Sewaralthahab K.
- Balk E.M.
- Eiam-ong S.
- Madias N.E.
- Jaber B.L.
Efficacy and safety of combined vs. single renin-angiotensin-aldosterone system blockade in chronic kidney disease: a meta-analysis.
Am J Hypertens. 2013; 26: 424-441- Rossignol P.
- Dobre D.
- McMurray J.J.V.
- et al.
Incidence, determinants, and prognostic significance of hyperkalemia and worsening renal function in patients with heart failure receiving the mineralocorticoid receptor antagonist eplerenone or placebo in addition to optimal medical therapy: results from the Eplerenone in Mild Patients Hospitalization and Survival Study in Heart Failure (EMPHASIS-HF).
Circ Heart Fail. 2014; 7: 51-58- Harel Z.
- Harel S.
- Shah P.S.
- Wald R.
- Perl J.
- Bell C.M.
Gastrointestinal adverse events with sodium polystyrene sulfonate (Kayexalate) use: a systematic review.
Am J Med. 2013; 126: 264.e9-264.e24Asking the question again: are cation exchange resins effective for the treatment of hyperkalemia?.
Nephrol Dial Transplant. 2012; 27: 4294-4297- Kosiborod M.
- Rasmussen H.S.
- Lavin P.
- et al.
Effect of sodium zirconium cyclosilicate on potassium lowering for 28 days among outpatients with hyperkalemia: the HARMONIZE randomized clinical trial.
JAMA. 2014; 312: 2223-2233- Paterson D.L.
- Robson J.M.
- Wagener M.M.
Risk factors for toxicity in elderly patients given aminoglycosides once daily.
J Gen Intern Med. 1998; 13: 735-739- Lodise T.P.
- Patel N.
- Lomaestro B.M.
- Rodvold K.A.
- Drusano G.L.
Relationship between initial vancomycin concentration-time profile and nephrotoxicity among hospitalized patients.
Clin Infect Dis. 2009; 49: 507-514Safety considerations of fluoroquinolones in the elderly: an update.
Drugs Aging. 2010; 27: 193-209- Hung C.C.
- Kuo M.C.
- Chang J.M.
- Chen H.C.
Fluoroquinolone-induced acute interstitial nephritis in immunocompromised patients: two case reports.
Nephrol Dial Transplant. 2006; 21: 237-238An evaluation of hyperkalemia and serum creatinine elevation associated with different dosage levels of outpatient trimethoprim-sulfamethoxazole with and without concomitant medications.
Ann Pharmacother. 2013; 47: 1618-1626- Antoniou T.
- Gomes T.
- Juurlink D.N.
- Loutfy M.R.
- Glazier R.H.
- Mamdani M.M.
Trimethoprim-sulfamethoxazole-induced hyperkalemia in patients receiving inhibitors of the renin-angiotensin system: a population-based study.
Arch Intern Med. 2010; 170: 1045-1049- Antoniou T.
- Gomes T.
- Mamdani M.M.
- Juurlink D.N.
Trimethoprim/sulfamethoxazole-induced phenytoin toxicity in the elderly: a population-based study.
Br J Clin Pharmacol. 2011; 71: 544-549- Wright A.J.
- Gomes T.
- Mamdani M.M.
- Horn J.R.
- Juurlink D.N.
The risk of hypotension following co-prescription of macrolide antibiotics and calcium-channel blockers.
CMAJ. 2011; 183: 303-307- Rallidis L.S.
- Fountoulaki K.
- Anastasiou-Nana M.
Man ageing the underestimated risk of statin-associated myopathy.
Int J Cardiol. 2012; 159: 169-176- Chan A.L.
- Wang M.T.
- Su C.Y.
- Tsai F.H.
Risk of digoxin intoxication caused by clarithromycin-digoxin interactions in heart failure patients: a population-based study.
Eur J Clin Pharmacol. 2009; 65: 1237-1243- Shorr R.I.
- Ray W.A.
- Daugherty J.R.
- Griffin M.R.
Concurrent use of nonsteroidal anti-inflammatory drugs and oral anticoagulants places elderly persons at high risk for hemorrhagic peptic ulcer disease.
Arch Intern Med. 1993; 153: 1665-1670- Brodsky S.V.
- Nadasdy T.
- Rovin B.H.
- et al.
Warfarin-related nephropathy occurs in patients with and without chronic kidney disease and is associated with an increased mortality rate.
Kidney Int. 2011; 80: 181-189- Taksande S.R.
- Worcester E.M.
Calcium supplementation in chronic kidney disease.
Expert Opin Drug Saf. 2014; 13: 1175-1185- Rej S.
- Herrmann N.
- Shulman K.
The effects of lithium on renal function in older adults—a systematic review.
J Geriatr Psychiatry Neurol. 2012; 25: 51-61- Bocchetta A.
- Ardau R.
- Carta P.
- et al.
Duration of lithium treatment is a risk factor for reduced glomerular function: a cross-sectional study.
BMC Med. 2013; 11: 33- Zaidan M.
- Stucker F.
- Stengel B.
- et al.
Increased risk of solid renal tumors in lithium-treated patients.
Kidney Int. 2014; 86: 184-190- Hanchard B.
- Boulouffe C.
- Vanpee D.
Sulfonylurea-induced hypoglycaemia: use of octreotide.
Acta Clin Belg. 2009; 64: 56-58Benefits and risks with glyburide and glipizide in elderly NIDDM patients.
Diabetes Care. 1992; 15: 75-80- Stades A.M.E.
- Heikens J.T.
- Erkelens D.W.
- Holleman F.
- Hoekstra J.B.
Metformin and lactic acidosis: cause or coincidence? A review of case reports.
J Intern Med. 2004; 255: 179-187- Nathan D.M.
- Buse J.B.
- Davidson M.B.
- et al.
- American Diabetes Association; European Association for Study of Diabetes
Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes.
Diabetes Care. 2009; 32: 193-203- Elmore L.K.
- Baggett S.
- Kyle J.A.
- Skelley J.W.
A review of the efficacy and safety of canagliflozin in elderly patients with type 2 diabetes.
Consult Pharm. 2014; 29: 335-346- Tinetti M.E.
- Han L.
- Lee D.S.
- et al.
Antihypertensive medications and serious fall injuries in a nationally representative sample of older adults.
JAMA Intern Med. 2014; 174: 588-595- Andersson C.
- Shilane D.
- Go A.S.
- et al.
β-Blocker therapy and cardiac events among patients with newly diagnosed coronary heart disease.
J Am Coll Cardiol. 2014; 64: 247-252Atenolol vs nonatenolol β-blockers for the treatment of hypertension: a meta-analysis.
Can J Cardiol. 2014; 30: S47-S53- Stason W.B.
- Schmid C.H.
- Niedzwiecki D.
- et al.
Safety of nifedipine in patients with hypertension: a meta-analysis.
Hypertension. 1997; 30 (): 7-14- Jung S.Y.
- Choi N.K.
- Kim J.Y.
- et al.
Short-acting nifedipine and risk of stroke in elderly hypertensive patients.
Neurology. 2011; 77: 1229-1234- Miyagawa K.
- Dohi Y.
- Nakazawa A.
- et al.
Renoprotective effect of calcium channel blockers in combination with an angiotensin receptor blocker in elderly patients with hypertension: a randomized crossover trial between benidipine and amlodipine.
Clin Exp Hypertens. 2010; 32: 1-7- Fliser D.
- Schröter M.
- Neubeck M.
- Ritz E.
Coadministration of thiazides increases the efficacy of loop diuretics even in patients with advanced renal failure.
Kidney Int. 1994; 46: 482-488- Harper C.R.
- Jacobson T.A.
Managing dyslipidemia in chronic kidney disease.
J Am Coll Cardiol. 2008; 51: 2375-2384- Takenaka T.
- Takane H.
- Kikuta T.
- Watanabe Y.
- Suzuki H.
Statin improves flow-mediated vasodilation in chronic kidney diseases.
Int J Hypertens. 2013; 2013: 876865- Baigent C.
- Landray M.J.
- Reith C.
- et al.
- SHARP Investigators
The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.
Lancet. 2011; 377: 2181-2192- Palmer S.C.
- Navaneethan S.D.
- Craig J.C.
- et al.
HMG CoA reductase inhibitors (statins) for people with chronic kidney disease not requiring dialysis.
Cochrane Database Syst Rev. 2014; 5: CD007784- Sattar N.
- Preiss D.
- Murray H.M.
- et al.
Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials.
Lancet. 2010; 375: 735-742- Bilge U.
- Sahin G.
- Unluoglu I.
- Ipek M.
- Durdu M.
- Keskin A.
Inappropriate use of nonsteroidal anti-inflammatory drugs and other drugs in chronic kidney disease patients without renal replacement therapy.
Ren Fail. 2013; 35: 906-910- Schneider V.
- Lévesque L.E.
- Zhang B.
- Hutchinson T.
- Brophy J.M.
Association of selective and conventional nonsteroidal antiinflammatory drugs with acute renal failure: a population-based, nested case-control analysis.
Am J Epidemiol. 2006; 164: 881-889Use of diuretics with ACE inhibitors or angiotensin receptor blockers and NSAIDs increases the risk of acute kidney injury.
Evid Based Med. 2013; 18: 232-233- Kikuchi H.
- Aoyagi M.
- Nagahama K.
- et al.
Nephrotic-range proteinuria and interstitial nephritis associated with the use of a topical loxoprofen patch.
Intern Med. 2014; 53: 1131-1135- American Geriatrics Society Panel on Pharmacological Management of Persistent Pain in Older Persons
Pharmacological management of persistent pain in older persons.
J Am Geriatr Soc. 2009; 57: 1331-1346- Robson R.
- Cecka J.M.
- Opelz G.
- Budde M.
- Sacks S.
Prospective registry-based observational cohort study of the long-term risk of malignancies in renal transplant patients treated with mycophenolate mofetil.
Am J Transplant. 2005; 5: 2954-2960Risk factors for cyclosporine-induced nephropathy in patients with autoimmune diseases. International Kidney Biopsy Registry of Cyclosporine in Autoimmune Diseases.
N Engl J Med. 1992; 326: 1654-1660Immunotherapy in elderly transplant recipients: a guide to clinically significant drug interactions.
Drugs Aging. 2009; 26: 715-737- Nankivell B.J.
- Murali K.M.
Images in clinical medicine: renal failure from vitamin C after transplantation.
N Engl J Med. 2008; 358: e4Circulating retinol-binding protein 4 and subclinical cardiovascular disease in the elderly.
Diabetes Care. 2009; 32: 733-735- Henze A.
- Frey S.K.
- Raila J.
- et al.
Evidence that kidney function but not type 2 diabetes determines retinol-binding protein 4 serum levels.
Diabetes. 2008; 57: 3323-3326- Ravani P.
- Malberti F.
- Tripepi G.
- et al.
Vitamin D levels and patient outcome in chronic kidney disease.
Kidney Int. 2009; 75: 88-95- Yu E.W.
- Bauer S.R.
- Bain P.A.
- Bauer D.C.
Proton pump inhibitors and risk of fractures: a meta-analysis of 11 international studies.
Am J Med. 2011; 124: 519-526Adverse effects of proton pump inhibitor drugs: clues and conclusions.
Curr Opin Gastroenterol. 2010; 26: 624-631- Corsonello A.
- Maggio M.
- Fusco S.
- et al.
Proton pump inhibitors and functional decline in older adults discharged from acute care hospitals.
J Am Geriatr Soc. 2014; 62: 1110-1115- Luk C.P.
- Parsons R.
- Lee Y.P.
- Hughes J.D.
Proton pump inhibitor-associated hypomagnesemia: what do FDA data tell us?.
Ann Pharmacother. 2013; 47: 773-780- Klepser D.G.
- Collier D.S.
- Cochran G.L.
Proton pump inhibitors and acute kidney injury: a nested case-control study.
BMC Nephrol. 2013; 14: 150- Liamis G.
- Milionis H.
- Elisaf M.
A review of drug-induced hyponatremia.
Am J Kidney Dis. 2008; 52: 144-153Hyponatraemia and selective serotonin re-uptake inhibitors in elderly patients.
Int J Geriatr Psychiatry. 2001; 16: 484-493- Zalai D.
- Szeifert L.
- Novak M.
Psychological distress and depression in patients with chronic kidney disease.
Semin Dial. 2012; 25: 428-438- Harugeri A.
- Joseph J.
- Parthasarathi G.
- Ramesh M.
- Guido S.
Potentially inappropriate medication use in elderly patients: a study of prevalence and predictors in two teaching hospitals.
J Postgrad Med. 2010; 56: 186-191- Schaeffner E.S.
- Ebert N.
- Delanaye P.
- et al.
Two novel equations to estimate kidney function in persons aged 70 years or older.
Ann Intern Med. 2012; 157: 471-481- Doak M.W.
- Nixon A.C.
- Lupton D.J.
- Waring W.S.
Self-poisoning in older adults: patterns of drug ingestion and clinical outcomes.
Age Ageing. 2009; 38: 407-411- Barry P.J.
- Gallagher P.
- Ryan C.
- O’mahony D.
START (screening tool to alert doctors to the right treatment)—an evidence-based screening tool to detect prescribing omissions in elderly patients.
Age Ageing. 2007; 36: 632-638- Claxton A.J.
- Cramer J.
- Pierce C.
A systematic review of the associations between dose regimens and medication compliance.
Clin Ther. 2001; 23: 1296-1310- Qato D.M.
- Alexander G.C.
- Conti R.M.
- Johnson M.
- Schumm P.
- Lindau S.T.
Use of prescription and over-the-counter medications and dietary supplements among older adults in the United States.
JAMA. 2008; 300: 2867-2878