In the article “Lipoprotein(a), Cardiovascular Disease, and Contemporary Management,” published in the November 2013 issue of Mayo Clinic Proceedings (2013;88(11):1294-1311), Lp(a) cholesterol and Lp(a)-C should read as Lp(a) throughout the article.
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© 2014 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.
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- Lipoprotein(a), Cardiovascular Disease, and Contemporary ManagementMayo Clinic ProceedingsVol. 88Issue 11
- PreviewElevated lipoprotein(a) (Lp[a]) is a causal genetic risk factor for cardiovascular disease. To determine if current evidence supports both screening and treatment for elevated Lp(a) in high-risk patients, an English-language search of PubMed and MEDLINE was conducted. In population studies, there is a continuous association between Lp(a) concentrations and cardiovascular risk, with synergistic effects when low-density lipoprotein (LDL) is also elevated. Candidates for Lp(a) screening include patients with a personal or family history of premature cardiovascular disease, familial hypercholesterolemia, recurrent cardiovascular events, or inadequate LDL cholesterol (LDL-C) responses to statins.
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