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Magnetic Resonance Imaging of the Heart: Current Status

      The favorable technical capabilities of magnetic resonance imaging (MRI) make it well suited for delineating the heart and great vessels. The clinical applications of cardiac MRI have gradually expanded in the past several years. Currently, the most important applications use the modality to provide detailed morphologic information, especially about surgical lesions of the heart. Particularly noteworthy have been applications of MRI in preoperative assessment of patients with certain types of congenital heart disease, cardiac masses, and lesions of the great vessels. Other roles for the modality such as in functional cardiac imaging and nuclear magnetic resonance spectroscopy remain attractive, but these have not yet entered the domain of routine clinical practice.
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      REFERENCES

        • Bloch F
        • Hansen WW
        • Packard M
        Nuclear induction (letter to the editor).
        Phys Rev. 1946; 69: 127
        • Purcell EM
        • Torrey HC
        • Pound RV
        Resonance absorption by nuclear magnetic moments in a solid (letter to the editor).
        Phys Rev. 1946; 69: 37-38
        • Lauterbur PC
        Image formation by induced local interactions: examples employing nuclear magnetic resonance (letter to the editor).
        Nature. 1973; 242: 190-191
      1. Damadian R: Apparatus and method for detecting cancer in tissue. US Patent 3,789,832, Mar 17, 1972

        • Damadian R
        • Goldsmith M
        • Minkoff L
        NMR in cancer. XVI. Fonar image of the live human body.
        Physiol Chem Phys. 1977; 9: 97-100
        • Lanzer P
        • Botvinick EH
        • Schiller NB
        • Crooks LE
        • Arakawa M
        • Kaufman L
        • Davis PL
        • Herfkens R
        • Lipton MJ
        • Higgins CB
        Cardiac imaging using gated magnetic resonance.
        Radiology. 1984; 150: 121-127
        • Crooks LE
        • Barker B
        • Chang H
        • Feinberg D
        • Hoenninger JC
        • Watts JC
        • Arakawa M
        • Kaufman L
        • Sheldon PE
        • Botvinick E
        • Higgins CB
        Magnetic resonance imaging strategies for heart studies.
        Radiology. 1984; 153: 459-465
        • Lanzer P
        • Barta C
        • Botvinick EH
        • Wiesendanger HUD
        • Modin G
        • Higgins CB
        ECG-synchronized cardiac MR imaging: method and evaluation.
        Radiology. 1985; 155: 681-686
        • Herfkens RJ
        • Higgins CB
        • Hricak H
        • Lipton MJ
        • Crooks LE
        • Lanzer P
        • Botvinick E
        • Brundage B
        • Sheldon PE
        • Kaufman L
        Nuclear magnetic resonance imaging of the cardiovascular system: normal and pathologic findings.
        Radiology. 1983; 147: 749-759
        • Feiglin DH
        • George CR
        • MacIntyre WJ
        • O'Donnell JK
        • Go RT
        • Pavlicek W
        • Meaney TF
        Gated cardiac magnetic resonance structural imaging: optimization by electronic axial rotation.
        Radiology. 1985; 154: 129-132
        • Higgins CB
        MR of the heart: anatomy, physiology, and metabolism.
        AJR. 1988; 151: 239-248
        • Dinsmore RE
        • Wismer GL
        • Levine RA
        • Okada RD
        • Brady TJ
        Magnetic resonance imaging of the heart: positioning and gradient angle selection for optimal imaging planes.
        AJR. 1984; 143: 1135-1142
        • Dinsmore RE
        • Wismer GL
        • Miller SW
        • Thompson R
        • Johnston DL
        • Liu P
        • Okada RD
        • Saini S
        • Brady TJ
        Magnetic resonance imaging of the heart using image planes oriented to cardiac axes: experience with 100 cases.
        AJR. 1985; 145: 1177-1183
        • Haase A
        • Frahm J
        • Matthaei D
        • Hänicke W
        • Merboldt K-D
        FLASH imaging: rapid NMR imaging using low flip-angle pulses.
        J Magn Reson. 1986; 67: 258-266
        • Sechtem U
        • Pflugfelder PW
        • White RD
        • Gould RG
        • Holt W
        • Lipton MJ
        • Higgins CB
        Cine MR imaging: potential for the evaluation of cardiovascular function.
        AJR. 1987; 148: 239-246
        • Utz JA
        • Herfkens RJ
        • Heinsimer JA
        • Bashore T
        • Califf R
        • Glover G
        • Pelc N
        • Shimakawa A
        Cine MR determination of left ventricular ejection fraction.
        AJR. 1987; 148: 839-843
        • Schiebler M
        • Axel L
        • Reichek N
        • Aurigemma G
        • Yeager B
        • Douglas P
        • Bogin K
        • Kressel H
        Correlation of cine MR imaging with two-dimensional pulsed Doppler echocardiography in valvular insufficiency.
        J Comput Assist Tomogr. 1987; 11: 627-632
        • Sechtem U
        • Pflugfelder P
        • Cassidy MC
        • Holt W
        • Wolfe C
        • Higgins CB
        Ventricular septal defect: visualization of shunt flow and determination of shunt size by cine MR imaging.
        AJR. 1987; 149: 689-692
        • Rzedzian RR
        • Pykett IL
        Instant images of the human heart using a new, whole-body MR imaging system.
        AJR. 1987; 149: 245-250
        • Felmlee JP
        • Ehman RL
        Spatial presaturation: a method for suppressing flow artifacts and improving depiction of vascular anatomy in MR imaging.
        Radiology. 1987; 164: 559-564
        • Soulen RL
        • Budinger TF
        • Higgins CB
        Magnetic resonance imaging of prosthetic heart valves.
        Radiology. 1985; 154: 705-707
        • Fletcher BD
        • Jacobstein MD
        • Nelson AD
        • Riemenschneider TA
        • Alfidi RJ
        Gated magnetic resonance imaging of congenital cardiac malformations.
        Radiology. 1984; 150: 137-140
        • Didier D
        • Higgins CB
        • Fisher MR
        • Osaki L
        • Silverman NH
        • Cheitlin MD
        Congenital heart disease: gated MR imaging in 72 patients.
        Radiology. 1986; 158: 227-235
        • Guit GL
        • Bluemm R
        • Rohmer J
        • Wenink AC
        • Chin JG
        • Doornbos J
        • van Voorthuisen AE
        Levotransposition of the aorta: identification of segmental cardiac anatomy using MR imaging.
        Radiology. 1986; 161: 673-679
        • Fletcher BD
        • Jacobstein MD
        • Abramowsky CR
        • Anderson RH
        Right atrioventricular valve atresia: anatomic evaluation with MR imaging.
        AJR. 1987; 148: 671-674
        • Diethelm L
        • Déry R
        • Lipton MJ
        • Higgins CB
        Atrial-level shunts: sensitivity and specificity of MR in diagnosis.
        Radiology. 1987; 162: 181-186
      2. Julsrud PR, Ehman RL, Hagler DJ, Ilstrup DM: Magnetic resonance imaging of Fontan candidates. Radiology (in press)

        • Amparo EG
        • Higgins CB
        • Farmer D
        • Gamsu G
        • McNamara M
        Gated MRI of cardiac and paracardiac masses: initial experience.
        AJR. 1984; 143: 1151-1156
        • Conces Jr, DJ
        • Vix VA
        • Klatte EC
        Gated MR imaging of left atrial myxomas.
        Radiology. 1985; 156: 445-447
        • Go RT
        • O'Donnell JK
        • Underwood DA
        • Feiglin DH
        • Salcedo EE
        • Pantoja M
        • MacIntyre WJ
        • Meaney TF
        Comparison of gated cardiac MRI and 2D echocardiography of intracardiac neoplasms.
        AJR. 1985; 145: 21-25
        • Winkler M
        • Higgins CB
        Suspected intracardiac masses: evaluation with MR imaging.
        Radiology. 1987; 165: 117-122
        • Lund JT
        • Ehman RL
        • Julsrud PR
        • Sinak LJ
        • Tajik AJ
        Cardiac masses: assessment by MR imaging.
        AJR. 1989; 152: 469-473
        • Sechtem U
        • Tscholakoff D
        • Higgins CB
        MRI of the normal pericardium.
        AJR. 1986; 147: 239-244
        • Sechtem U
        • Tscholakoff D
        • Higgins CB
        MRI of the abnormal pericardium.
        AJR. 1986; 147: 245-252
        • Soulen RL
        • Stark DD
        • Higgins CB
        Magnetic resonance imaging of constrictive pericardial disease.
        Am J Cardiol. 1985; 55: 480-484
        • Higgins CB
        • Byrd III, BF
        • Stark D
        • McNamara M
        • Lanzer P
        • Lipton MJ
        • Schiller NB
        • Botvinick E
        • Chatterjee K
        Magnetic resonance imaging in hypertrophic cardiomyopathy.
        Am J Cardiol. 1985; 55: 1121-1126
        • Winkler ML
        • Higgins CB
        MRI of perivalvular infectious pseudoaneurysms.
        AJR. 1986; 147: 253-256
        • White RD
        • Ullyot DJ
        • Higgins CB
        MR imaging of the aorta after surgery for aortic dissection.
        AJR. 1988; 150: 87-92
        • Kersting-Sommerhoff BA
        • Higgins CB
        • White RD
        • Sommerhoff CP
        • Lipton MJ
        Aortic dissection: sensitivity and specificity of MR imaging.
        Radiology. 1988; 166: 651-655
        • Glazer HS
        • Gutierrez FR
        • Levitt RG
        • Lee JKT
        • Murphy WA
        The thoracic aorta studied by MR imaging.
        Radiology. 1985; 157: 149-155
        • Geisinger MA
        • Risius B
        • O'Donnell JA
        • Zelch MG
        • Moudie DS
        • Graor RA
        • George CR
        Thoracic aortic dissections: magnetic resonance imaging.
        Radiology. 1985; 155: 407-412
        • Wesbey GE
        • Higgins CB
        • McNamara MT
        • Engelstad BL
        • Lipton MJ
        • Sievers R
        • Ehman RL
        • Lovin J
        • Brasch RC
        Effect of gadolinium-DTPA on the magnetic relaxation times of normal and infarcted myocardium.
        Radiology. 1984; 153: 165-169
        • Yamada T
        • Tada S
        • Harada J
        Aortic dissection without intimal rupture: diagnosis with MR imaging and CT.
        Radiology. 1988; 168: 347-352
        • Bank ER
        • Aisen AM
        • Rocchini AP
        • Hernandez RJ
        Coarctation of the aorta in children undergoing angioplasty: pretreatment and posttreatment MR imaging.
        Radiology. 1987; 162: 235-240
        • Von Schulthess GK
        • Higashino SM
        • Higgins SS
        • Didier D
        • Fisher MR
        • Higgins CB
        Coarctation of the aorta: MR imaging.
        Radiology. 1986; 158: 469-474
        • Gomes AS
        • Lois JF
        • George B
        • Alpan G
        • Williams RG
        Congenital abnormalities of the aortic arch: MR imaging.
        Radiology. 1987; 165: 691-695
        • Bisset III, GS
        • Strife JL
        • Kirks DR
        • Bailey WW
        Vascular rings: MR imaging.
        AJR. 1987; 149: 251-256
        • Soulen RL
        • Fishman EK
        • Pyeritz RE
        • Zerhouni EA
        • Pessar ML
        Marfan syndrome: evaluation with MR imaging versus CT.
        Radiology. 1987; 165: 697-701
        • Fisher MR
        • von Schulthess GK
        • Higgins CB
        Multiphasic cardiac magnetic resonance imaging: normal regional left ventricular wall thickening.
        AJR. 1985; 145: 27-30
        • Stratemeier EJ
        • Thompson R
        • Brady TJ
        • Miller SW
        • Saini S
        • Wismer GL
        • Okada RD
        • Dinsmore RE
        Ejection fraction determination by MR imaging: comparison with left ventricular angiography.
        Radiology. 1986; 158: 775-777
        • Rehr RB
        • Malloy CR
        • Filipchuk NG
        • Peshock RM
        Left ventricular volumes measured by MR imaging.
        Radiology. 1985; 156: 717-719
        • Longmore DB
        • Klipstein RH
        • Underwood SR
        • Firmin DN
        • Hounsfield GN
        • Watanabe M
        • Bland C
        • Fox K
        • Poole-Wilson PA
        • Rees RSO
        • Denison D
        • McNeilly AM
        • Burman ED
        Dimensional accuracy of magnetic resonance in studies of the heart.
        Lancet. 1985; 1: 1360-1362
        • Sechtem U
        • Pflugfelder PW
        • Gould RG
        • Cassidy MM
        • Higgins CB
        Measurement of right and left ventricular volumes in healthy individuals with cine MR imaging.
        Radiology. 1987; 163: 697-702
        • Utz JA
        • Herfkens RJ
        • Heinsimer JA
        • Shimakawa A
        • Glover G
        • Pelc N
        Valvular regurgitation: dynamic MR imaging.
        Radiology. 1988; 168: 91-94
        • Pflugfelder PW
        • Sechtem UP
        • White RD
        • Higgins CB
        Quantification of regional myocardial function by rapid cine MR imaging.
        AJR. 1988; 150: 523-529
        • Sechtem U
        • Pflugfelder PW
        • Cassidy MM
        • White RD
        • Cheitlin MD
        • Schiller NB
        • Higgins CB
        Mitral or aortic regurgitation: quantification of regurgitant volumes with cine MR imaging.
        Radiology. 1988; 167: 425-430
        • White RD
        • Pflugfelder PW
        • Lipton MJ
        • Higgins CB
        Coronary artery bypass grafts: evaluation of patency with cine MR imaging.
        AJR. 1988; 150: 1271-1274
        • Gomes AS
        • Lois JF
        • Drinkwater Jr, DC
        • Corday SR
        Coronary artery bypass grafts: visualization with MR imaging.
        Radiology. 1987; 162: 175-179
        • White RD
        • Caputo GR
        • Mark AS
        • Modin GW
        • Higgins CB
        Coronary artery bypass graft patency: noninvasive evaluation with MR imaging.
        Radiology. 1987; 164: 681-686
        • Bateman TM
        • Gray RJ
        • Whiting JS
        • Sethna DH
        • Berman DS
        • Matloff JM
        • Swan HJC
        • Forrester JS
        Prospective evaluation of ultrafast cardiac computed tomography for determination of coronary bypass graft patency.
        Circulation. 1987; 75: 1018-1024
        • Zerhouni EA
        • Parish DM
        • Rogers WJ
        • Yang A
        • Shapiro EP
        Human heart: tagging with MR imaging—a method for noninvasive assessment of myocardial motion.
        Radiology. 1988; 169: 59-63
        • Wesbey G
        • Higgins CB
        • Lanzer P
        • Botvinick E
        • Lipton MJ
        Imaging and characterization of acute myocardial infarction in vivo by gated nuclear magnetic resonance.
        Circulation. 1984; 69: 125-130
        • Pflugfelder PW
        • Wisenberg G
        • Prato FS
        • Carroll SE
        • Turner KL
        Early detection of canine myocardial infarction by magnetic resonance imaging in vivo.
        Circulation. 1985; 71: 587-594
        • Rokey R
        • Verani MS
        • Bolli R
        • Kuo LC
        • Ford JJ
        • Wendt RE
        • Schneiders NJ
        • Bryan RN
        • Roberts R
        Myocardial infarct size quantification by MR imaging early after coronary artery occlusion in dogs.
        Radiology. 1986; 158: 771-774
        • Caputo GR
        • Sechtem U
        • Tscholakoff D
        • Higgins CB
        Measurement of myocardial infarct size at early and late time intervals using MR imaging: an experimental study in dogs.
        AJR. 1987; 149: 237-243
        • Tscholakoff D
        • Higgins CB
        • Sechtem U
        • McNamara MT
        Occlusive and reperfused myocardial infarcts: effect of Gd-DTPA on ECG-gated MR imaging.
        Radiology. 1986; 160: 515-519
        • McNamara MT
        • Higgins CB
        • Ehman RL
        • Revel D
        • Sievers R
        • Brasch RC
        Acute myocardial ischemia: magnetic resonance contrast enhancement with gadolinium-DTPA.
        Radiology. 1984; 153: 157-163
        • De Roos A
        • Doornbos J
        • van der Wall EE
        • van Voorthuisen AE
        MR imaging of acute myocardial infarction: value of Gd-DTPA.
        AJR. 1988; 150: 531-534
        • McNamara MT
        • Tscholakoff D
        • Revel D
        • Soulen R
        • Schechtmann N
        • Botvinick E
        • Higgins CB
        Differentiation of reversible and irreversible myocardial injury by MR imaging with and without gadolinium-DTPA.
        Radiology. 1986; 158: 765-769
        • Tscholakoff D
        • Aherne T
        • Yee ES
        • Derugin N
        • Higgins CB
        Cardiac transplantations in dogs: evaluation with MR.
        Radiology. 1985; 157: 697-702
        • Ehman RL
        • McNamara MT
        • Brasch RC
        • Felmlee JP
        • Gray JE
        • Higgins CB
        Influence of physiologic motion on the appearance of tissue in MR images.
        Radiology. 1986; 159: 777-782
        • Bottomley PA
        • Herfkens RJ
        • Smith LS
        • Bashore TM
        Altered phosphate metabolism in myocardial infarction: P-31 MR spectroscopy.
        Radiology. 1987; 165: 703-707
        • Dumoulin CL
        • Hart Jr, HR
        Magnetic resonance angiography.
        Radiology. 1986; 161: 717-720
        • Higgins CB
        New horizons in cardiac imaging.
        Radiology. 1985; 156: 577-588
        • Reiter SJ
        • Rumberger JA
        • Feiring AJ
        • Stanford W
        • Marcus ML
        Precision of measurements of right and left ventricular volume by cine computed tomography.
        Circulation. 1986; 74: 890-900
        • Feiring AJ
        • Rumberger JA
        • Reiter SJ
        • Skorton DJ
        • Collins SM
        • Lipton MJ
        • Higgins CB
        • Ell S
        • Marcus ML
        Determination of left ventricular mass in dogs with rapid-acquisition cardiac computed tomographic scanning.
        Circulation. 1985; 72: 1355-1364