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Management of Malignant Melanoma of the Head and Neck

      The management of malignant melanoma of the head and neck is based on results of excisional or incisional biopsy findings. The thickness of the lesion dictates the extent of reexcision of the biopsy site and the appropriateness of elective node dissection. Because narrow margins of excision are usually adequate, primary closure of the postoperative defect is often possible. At the Mayo Clinic, the 5-year survival of patients with stage I malignant melanoma of the head and neck has been 70%. Except for patients with extremely thin (noninvasive) melanomas, follow-up surveillance, including physical examination of the head and neck region and chest roentgenography, is important.
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      REFERENCES

        • Clark Jr, WH
        • From L
        • Bernardino EA
        • Mihm MC
        The histogenesis and biologic behavior of primary human malignant melanomas of the skin.
        Cancer Res. 1969; 29: 705-715
        • Breslow A
        Thickness, cross-sectional areas and depth of invasion in the prognosis of cutaneous melanoma.
        Ann Surg. 1970; 172: 902-908
        • Balch CM
        • Soong S-J
        • Milton GW
        • Shaw HM
        • McGovern VJ
        • Murad TM
        • McCarthy WH
        • Maddox WA
        A comparison of prognostic factors and surgical results in 1,786 patients with localized (stage I) melanoma treated in Alabama, USA, and New South Wales, Australia.
        Ann Surg. 1982; 196: 677-684
        • Wanebo HJ
        • Harpole D
        • Teates CD
        Radionuclide lymphoscintigraphy with technetium 99m antimony sulfide colloid to identify lymphatic drainage of cutaneous melanoma at ambiguous sites in the head and neck and trunk.
        Cancer. 1985; 55: 1403-1413
        • Milton GW
        • Shaw HM
        • McCarthy WH
        • Pearson L
        • Balch CM
        • Soong SJ
        Prophylactic lymph node dissection in clinical stage I cutaneous malignant melanoma: results of surgical treatment in 1319 patients.
        Br J Surg. 1982; 69: 108-111
        • Reintgen DS
        • Cox EB
        • McCarty Jr, KS
        • Vollmer RT
        • Seigler HF
        Efficacy of elective lymph node dissection in patients with intermediate thickness primary melanoma.
        Ann Surg. 1983; 198: 379-384
        • Wanebo HJ
        • Woodruff J
        • Fortner JG
        Malignant melanoma of the extremities: a clinicopathologic study using levels of invasion (microstage).
        Cancer. 1975; 35: 666-676
        • Turkula LD
        • Woods JE
        Limited or selective nodal dissection for malignant melanoma of the head and neck.
        Am J Surg. 1984; 148: 446-448
        • Byers RM
        The role of modified neck dissection in the treatment of cutaneous melanoma of the head and neck.
        Arch Surg. 1986; 121: 1338-1340
        • Thayer Jr, JO
        • Overholt RH
        Metastatic melanoma to the lung: long-term results of surgical excision.
        Am J Surg. 1985; 149: 558-561
        • Wornom III, IL
        • Smith JW
        • Soong S-J
        • McElvein R
        • Urist MM
        • Balch CM
        Surgery as palliative treatment for distant metastases of melanoma.
        Ann Surg. 1986; 204: 181-185
        • Hamaker RC
        • Conley J
        Melanoma of the head and neck.
        in: Ariel IM Malignant Melanoma. Appleton-Century-Crofts, New York1981: 291-302
        • Reiman HM
        • Goellner JR
        • Woods JE
        • Mixter RC
        Desmoplastic melanoma of the head and neck.
        Cancer. 1987; 60: 2269-2274
        • Sim FH
        • Taylor WF
        • Creagan ET
        • Woods JE
        • Soule EH
        Melanoma in the midwestern United States: experience at the Mayo Clinic.
        in: Balch CM Milton GW Cutaneous Melanoma: Clinical Management and Treatment Results Worldwide. JB Lippincott Company, Philadelphia1985: 431-436