The safety and efficacy of a novel coronary atherectomy device were evaluated in the
first 50 patients who underwent 53 such procedures at the Mayo Clinic. This treatment
was used for atheromatous lesions in 27 patients and for restenosis after percutaneous
transluminal coronary angioplasty in 23; in 3 patients, it was repeated for recurrent
stenosis (2) or a persistent intimal flap (1). Successful results, defined as a reduction
of the stenosis by 40% or more in association with removal of tissue, absence of Q-wave
infarction, and no need for a bypass surgical procedure during in-hospital follow-up,
were achieved in 47 of the 53 procedures (89%). Atherectomy reduced the stenoses from
a mean of 87% to 15%. Failures occurred in 6 of the 53 procedures (11%). Three of
these patients subsequently underwent successful conventional balloon angioplasty,
and three required surgical treatment. Six patients had minor complications—embolization
of atheromatous material in two, intimal dissection in two, and side-branch occlusion
and transient thrombosis in one each. Coronary atherectomy with use of this device
promises to be a relatively safe and efficient treatment of coronary artery stenosis.
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REFERENCES
- Nonoperative dilatation of coronary-artery stenosis: percutaneous transluminal coronary angioplasty.N Engl J Med. 1979; 301: 61-68
- Restenosis after percutaneous transluminal coronary angioplasty: the Emory University Hospital experience.Am J Cardiol. 1987; 60: 39B-43B
- Restenosis after multilesion percutaneous transluminal coronary angioplasty.Am J Cardiol. 1987; 60: 44B-47B
- The Frankfurt experience in restenosis after coronary angioplasty.Am J Cardiol. 1987; 60: 48B-49B
- Restenosis after successful percutaneous transluminal coronary angioplasty: the Montreal Heart Institute experience.Am J Cardiol. 1987; 60: 50B-55B
- Coumadin and aspirin in prevention of recurrence after transluminal coronary angioplasty: a randomized study.Circulation. 1984; 69: 721-727
- Recurrence of stenosis after successful percutaneous transluminal coronary angioplasty (PTCA) (abstract).Circulation. 1982; 66: II331
- Restenosis after percutaneous transluminal coronary angioplasty (PTCA): a report from the PTCA Registry of the National Heart, Lung, and Blood Institute.Am J Cardiol. 1984; 53: 77C-81C
- Restenosis after successful coronary angioplasty in patients with single-vessel disease.Circulation. 1986; 73: 710-717
- Transluminal coronary atherectomy (TCA): results in 21 human cadaver vascular segments (abstract).Circulation. 1986; 74: II202
- Transluminal atherectomy: initial clinical results in 27 patients (abstract).Circulation. 1986; 74: II203
- Percutaneous coronary atherectomy (abstract).J Am Coll Cardiol. 1988; 11: 110A
- Transluminal atherectomy: early results in the treatment of atherosclerosis (abstract).J Am Coll Cardiol. 1988; 11: 109A
- Percutaneous coronary atherectomy (abstract).Circulation. 1988; 78: II82
- Transluminal peripheral atherectomy (abstract).Circulation. 1988; 78: II416
- Balloon angioplasty in multivessel coronary artery disease.Mayo Clin Proc. 1983; 58: 563-567
- Follow-up clinical results in patients undergoing percutaneous transluminal coronary angioplasty.Circulation. 1985; 71: 754-760
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© 1989 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.
