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Endocrine Mechanisms in Hypertension

      This text is the second volume in a series entitled “Perspectives in Hypertension.” The book begins with discussions of the traditional hypertensive endocrine syndromes, including those of glucocorticoid and mineralocorticoid excess and pheochromocytoma. In addition, the mechanisms of hypertension in disorders of thyroid hormone imbalance, diabetes, and obesity are reviewed. Separate chapters are devoted to the treatment of hypertension in patients with diabetes and to the possible special role of altered glomerular hemodynamics in the causation of diabetic nephropathy. Three chapters deal with hypertension in pregnancy and discuss the possible influence of the renin system and prostaglandins in normal pregnancy and preeclampsia, as well as the anatomic development of the uteroplacental vascular bed and alterations that occur in hypertensive patients. The final eight chapters review the current understanding of several hormones that may play a role in dysregulation of blood pressure. An additional chapter discusses the rare syndrome of renin-producing tumors.
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