Abstract
Objective
To compare the long-term results of mastoscopic axillary lymph node dissection (MALND)
and conventional axillary lymph node dissection (CALND).
Patients and Methods
From January 1, 2003, through December 31, 2005, a group of 1027 consecutive patients
with operable breast cancer were randomly assigned to 1 of 2 study groups: MALND and
CALND. The median follow-up was 63 months. The primary end points of the study were
operative outcomes, complication reduction, function conservation, and cosmetics.
The secondary end points were disease-free and overall survival.
Results
The mean operative blood loss in the MALND group was less than in the CALND group
(P<.001). The patients who underwent MALND had less axillary pain, numbness or paresthesias,
and arm swelling (P<.001). The aesthetic appearance of the axilla in the MALND group was much better
than that in the CALND group (P=.001 at 6 months and P=.002 at 24 months). A significant difference was found between the 2 groups in distant
metastasis (P=.04). The disease-free survival rate was 64.5% in the MALND group and 60.8% in the
CALND group (P=.88). The overall survival rate was 81.7% in the MALND group and 78.6% in the CALND
group (P=.95).
Conclusion
Compared with CALND, MALND has advantages in operative outcomes, complication reduction,
function conservation, and cosmetics.
Abbreviations and Acronyms:
ALND (axillary lymph node dissection), CALND (conventional axillary lymph node dissection), MALND (mastoscopic axillary lymph node dissection)To read this article in full you will need to make a payment
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Article Info
Publication History
Published online: November 12, 2012
Footnotes
Grant Support: This work was supported by Capital Medical Development Fund.
Identification
Copyright
© 2012 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.
