In this article, we discuss antimicrobial regimens for both outpatient and inpatient
use in infants and children. A substantial number of pediatric patient visits annually
result in the prescribing of antimicrobial drugs. The emergence of bacteria resistant
to commonly used antimicrobial agents is a growing concern. Information on newer drugs
such as meropenem, which is active against penicillin-resistant Streptococcus pneumoniae
and gram-negative bacilli, and cefepime, which has activity against gramnegative bacilli
including Pseudomonas aeruginosa and against gram-positive cocci is also presented.
Management of patients with congenital or acquired immunodeficiencies continues to
be challenging in regard to the use of antimicrobial drugs to treat various fungal
and viral infections. New formulations of older drugs such as aerosolized tobramycin
and amphotericin B lipid complex are available. New antiviral agents have been approved,
most of which are antiretroviral agents. Childhood tuberculosis is an ongoing concern,
and regimens to treat Mycobacterium tuberculosis in children are discussed.
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Individual reprints of this article are not available. The entire Symposium on Antimicrobial Agents will be available for purchase as a bound booklet from the Proceedings Editorial Office at a later date.
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© 2000 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.
