This article reviews the current data on human papillomavirus as the cause of most
cervical cancer cases, data on the recently approved human papillomavirus vaccines,
and updated information concerning the Bethesda System for interpretation of Papanicolaou
test results. Current recommendations for surgical treatment, concurrent chemotherapy,
and radiation therapy and recent advances in systemic therapy for advanced or metastatic
cervical cancer are reviewed.
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© 2007 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.